Tag Archive for: antibodies

Under a new partnership, Plectonic Biotech will use Sonrai’s AI-powered multi-omics platform to speed up development of its Logybody cancer treatment technology. The approach aims to cut side effects and improve precision.

Therapeutic antibodies today represent a cornerstone of the treatment of various diseases including cancer, infectious, autoimmune, cardiovascular, haematological, metabolic, neurologic and ocular diseases, and make up a major proportion of blockbuster drugs with global sales of more than US$230bn in 2023.

Denmark’s complement system activator specialist Commit Biologics A/S has added  a €5.5m extension to its €16.5 seed financing. New investor Korys joined Novo Holdings and Bioqube Ventures.

CEO Dr Peter Sondermann © Tacalyx GmbH

Glycan target specialist Tacalyx GmbH expands its seed financing to €14m to advance its anti-TACA cancer therapies.

Neuroblastoma cells (green) in the adrenal gland. Cell nuclei are coloured blue. © Charité | Anja Heeren-Hagemann

Essential Pharma has acquired Renaissance Pharma Ltd to commercialise  the company’s Phase II program Hu14.18K322A in pedriatric high-risk neuroblastoma.

Antibodies get a second life with the right attachment (payload) (©Genmab A/S, Valby)

Genmab announced today that it will acquire privately held biotech company ProfoundBio for $1.8bn in cash. The deal is designed to help the Danish pharmaceutical company deepen its cancer pipeline with next-generation antibody-drug conjugate therapies where the company has already an inlicensing deal with former Synaffix´s ADC technology platform (which was acquired mid of 2023 by Lonza).

© crevis - stock.adobe.com

AVT03, a biosimilar candidate for osteoporosis treatment, showed promise in treating bone illnesses, according to results from a pharmacokinetic study by Alvotech SA.

Accelerating and derisking antibody drug development by early lead panel optimization. Picture:©Yumab GmbH

Antibody engineering?The development of therapeutic antibodies is a time and cost ­intensive process. Biological and physicochemical properties of the lead molecules ­influence almost every step in the development. Investing into antibody engineering and lead ­optimisation during early development pays off in later steps and does not only accelerate the programme, but also increases the chance of success.

agenX

Genmab and argenx have entered a multiyear collaboration bringing together capabilities to jointly discover, develop and commercialise antibody therapies.

Abb.: Tosoh

Chromatography methods and practical tips to simplify and reduce the costs of your processes