Entries by Thomas Gabrielczyk

Non-viral is better

Immunogenicity and limited gene transfer capacity can negatively affect the outcome of cell and gene therapies. European Biotechnology magazine spoke to Dr Dimitrios Laurin Wagner, Berlin Center for Advanced Therapies (BeCAT) and “Gene Editing for Cell Therapy” group leader at Charité, on new approaches that promise to overcome some limitations of current virus-based gene therapies.

Transformative innovation in drug development

The technological and pharmacological advances lead to an increase in the ­number of molecules for R&D that are challenging and difficult to manufacture. To improve ­clinical success, pharma and biotech companies are seeking innovative ways to accelerate progress and ­reduce scientific, economic, and delivery risks.