Minoryx Therapeutics SL has closed a €51m financing, including Series C equity financing and complementary bank debt to commercialise X-ALD drug leriglitazone.

G7 Climate, Energy and Environment Ministers have announced a wide range of actions to tackle “the triple global crisis of climate change, biodiversity loss and pollution".
 

An anti-idiotypic anti­body (anti-ID Ab) can recognise and bind to the idiotypic center of another antibody. Anti-idiotype antibodies are widely used in therapeutic drug development, such as immunogenicity assessments, pharmacokinetic/pharmacodynamics (PK/PD) studies, and vaccine development.

Ellipses Pharma and SunRock Biopharma enter into a licensing agreement for a first-in-class bifunctional HER3:TRAIL fusion protein set to eliminate solid tumours.

COVID-19 is the acute pandemic, while antimicrobial resistance (AMR) is a silent, pandemic. New data makes the AMR pandemic visible, with the first global study of AMR estimating that 1.27 million people die from AMR every year, making AMR the 12th-leading cause of death globally.

Hamburg-based CRO Evotec SE has inked a drug development partnership with Spanish Almirall SA in dematology.

Avantium NV will get a €3m EU funding for a feasibility study of the electrochemical conversion of CO2 to consumer products.

Biocatalysis expert Enzymaster (Germany, China, Singapore) has cashed in $45m to expand its production capacity of engineered biosynthetic enzymes.

The EU Commission has launched its final consultation on the deregulation of new breeding techniques in agriculture.

Hamburg-headquartered Evotec SE has extended and expanded its three-year-old partnership with Bristol Myers Squibb in targeted protein degradation ("molecular glue degraders") for an additional eight years. 

The small molecule degraders link an E3 ubiquitin ligase with the molecular target, mostly in cancer and autoimmunity indications. The interaction results in ubiquitination and subsequent degradation of the recruited protein and is hoped to provide a ong-lasting therapeutic effect.
Bristol Myers Squibb brings in a huge library of E3 ligase modulators. Under the terms of the agreement, both parties will leverage all of Evotec’s appropriate platforms as well as AI/ML-based drug discovery.
Under the new agreement, Evotec cashes in an upfront payment of $200m and is eglible to obtain up to $5bn in milestone payments and tiered royalties on product sales.