Tag Archive for: cancer

Good news for BioNTech SE: The safety study of the ADC BNT326/YL202 developed by MediLink Therapeutics, which was suspended by the FDA in mid-June, will continue.

The US Food & Drug Administration has granted accelerated approval to Adaptimmune’s Tecelra as the world’s first therapy with genetically engineered T cells to fight a solid tumour.

With an investment of its venture arm (BI-VF), Boehringer Ingelheim underlines its committment to expand the reach of cancer immune therapies. The Series A financing in Chinese Synthetica Pioneering that engineers oncolytic bacteria to deliver toxic payloads or modulators of the tumour environment to solid tumours follows an investment in T3 Pharmaceuticals.

Lu 177-dotatate (pink and orange) binds to somatostatin receptors (green) on neuroendocrine tumor cells (blue) and kills the cells through the release of radioactive  particles.@ NCI. Credit: Adapted from Frontiers in Oncology. January 2019. Front. Oncol. doi: 10.3389/fonc.201800663

ITM Isotope Technologies Munich SE has raised €188m ito boost radiopharma pipeline, contract manufacturing cpacity, and launch ITM-11.

© Mikael Häggström, M.D - wikipeedia.org

Swiss antibody specialist Memo Therapeutics AG has added CHF20m to  its Series C financing, bringing the total amount raised in the funding round to CHF 45 million.

© German cancer research centre/ University Heidelberg

Flagging of CAR-T cells with the B7H6 protein weakened the response to human leukaemia in models as it marks them for NK cell attack, German researchers report.

Klineo team has grown since its inception in 2021. © Kineo SAS

Paris-based Klineo SAS has raised €2M to speed up access to clinical trials for oncology patients using an AI platform.
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Structuren of Pub domain of RNF31. © RCBS protein data base

Oss-based oncology company Flindr Therapeutics BV has secured €20m  to advance it first-in-class RNF31 inhibitors, which destabilises E3 ubiquitin ligase.

Tip of the iceberg: Investigating in hart to treat indications like Glioblastoma and Pancreatic cancer, TME Pharma is hoping for proof of therapeutic superiority and many more indications to adress (©TME Pharma NV)

TME Pharma (France/Germany) announced that the US Food and Drug Administration (FDA) has granted Fast Track designation for NOX-A12 (olaptesed pegol), TME Pharma’s CXCL12 inhibitor, in combination with radiotherapy and bevacizumab for use in the treatment of the aggressive adult brain cancer glioblastoma.

Canadian Fusion Therapeutics Inc is utilising the advantages of alpha medical isotopes to develop targeted alpha therapies. The company uses targeting molecules, such as antibodies, armed with potent alpha emitting isotopes to precisely and effectively induce cancer cell death by induction of DNA double strand breaks. © Fusion Therapeutics Inc

British pharma giant AstraZeneca has announced to acquire radio-conjugate specialist Fusion Therapeutics Inc for US$2bn upfront.