Simplified presentation of freeze-drying cycle development including the boundaries of DoE. Picture: Vetter Pharma-Fertigung GmbH & Co. KG

As the global demand for injectables grows, so does the demand for innovative delivery systems. For lyophilised forms, dual-chamber systems offer advantages. They have been on the market since the mid-1980s, mainly for emergency or chronic medication. The systems have been developed for the convenience of the patients/caregivers, but they also offer benefits for the pharma/biotech companies in regards to low residual volume and increased API yield.

© ColiN00B / Pixabay

Oxford Nanopore Technologies has impressed Amgen with its genetic sequencing technology. The US biopharma major has invested £50m in the Oxford-based company.

© Henry Salomé via Wikimedia Commons

In a Series B financing round, INSERM spin-off Acticor Biotech has raised €15.3m from European and Asian investors. The new financing will go towards the launch off the first Phase II clinical trial of its lead candidate ACT017 in acute ischemic stroke. 

Multinational biotherapeutics company HiFiBiO Therapeutics announced that it has taken over early stage biotech H-Immune Therapeutics. With the acquisition of the French Atomic Energy Commission spin-out, HiFiBiO aims to strengthen its strategic focus on targetting differenct T cell subsets and combat cancer. 

© Roche

Roche has announced that in a Phase III trial, its antibody-drug conjugate Kadcyla showed improved invasive disease-free survival in breast cancer patients.

Picture: Thermo Fischer Scientific

Is synthetic biology on the cusp of unlocking the next industrial revolution? A major roadblock is the ability to synthesise DNA for R&D in ways that are both cheap and efficient. Established players in the field believe the answer lies in miniaturising standard chemical processes and running them in parallel systems. But the new kids on the block are betting on a completely new process that involves enzymes.

Targovax ASA has reported promising disease-free survival (DFS) data from Tg01 in resected pancreatic cancer.
Figure 1: Celonic project cell line development timelines. (All pictures: Celonic)

The demand for the fast and robust development of manufacturing cell lines is ever growing, with an increasing number of therapeutic proteins in development. To fulfill these needs, Celonic engineered the cell line kit CHOvolution, which equips users with everything required for the development of mammalian cell lines and provides an integrated support system for assistance.

Wearing a green scarf made of wood, the Finnish EC VP on Jobs, Growth, Investment and Competitiveness Jyrki Katainen presented the European Commission's updated bioeconomy action plan in Brussels: © Audiovisual Service of the EC

Six years after the European Commission created the world’s first bioeconomy strategy and action plan, it presented a new action plan aimed at moving faster towards a climate-neutral, sustainable, biobased industry.  

Immunologist Mireia Sospedra (back) and Paula Ojer-Tomas  members of the team that identified a new candidate autoantigen in multiple sclerosis.
© Neuroimmunology and Multiple Sclerosis Research, University Hospital Zurich, Switzerland

T cells target a bacterial variant of a human enzyme promoting autoimmune diseases such as Multiple Sclerosis (MS).