The vision of the new approach is to awake T effector cells through BH4, which antagonises mediators of the immunosuppressive tumorr microenvironment, to fight cancer. © IMBA

Researchers at Austrian IMBA have identified a well-known co-factor of amino acid synthesis and monoamine neurotransmitter synthesis to play a prominent role in the development of autoimmunity and cancer.

BIO-Europe networking party in Copenhagen. © BIOCOM AG

Gene and cell therapies, pediatric drugs, and formulation were just some hot topics discussed in a record number of B2B meetings at BIO-Europe in Copenhagen. 

Oxurion NV and Beta Therapeutics Inc have inked an R&D agreement aimed to develop new heparanase inhibitors to treat dry AMD.

Schematic of the three-step targeted delivery procedure used for the slippery micropropellers.
(1) Injection of the micropropellers into the vitreous humor of the eye. (2) Magnetically driven long-range propulsion of the micropropellers in the vitreous toward the retina. (3) Observation of the micropropellers at the target region near the surface of the retina by OCT.

German researchers have developed a drug delivery nanobot that can propel through the eye.

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In March, the 9th edition of the "European Biotechnology Science & Industry Guide" will be published and distributed at BIO Europe Spring conference 2019 in Vienna. The B2B handbook presents companies and institutions in the fields of Biotech, Biopharma, BioServices and BioManufacturing an ideal medium with which new customers and investors can find you. The previous edition can be found here.

ARGX-110 mode of action. © Argenx SE
Argenx SE announced it achieved an overall response rate of 92% in patients with AML with its anti-TNFSF7 (CD70) antibody cusatuzumab. 
Denali Therapeutics raised $250m through an Nasdaq IPO in December 2017. © Nasdaq

Sanofi has acquired the global commercialisation rights for two preclinical programmes from Denali Therapeutics.

Picture: Oxurion NV

Oxurion NV (formerly known as ThromboGenics NV), a biopharmaceutical company developing treatments to preserve vision in patients with diseases affecting the back of the eye, announced today the appointment of Adrienne Graves, Ph.D., to its board of directors. Dr. Graves will replace Paul Howes, who has been a board member since 2014.

Dutch ProQR NV has licensed global commercialisation rights to IONIS-RHO-2.5Rx (QR-1123) from Ionis Pharmaceuticals, to treat autosomal dominant retinitis pigmentosa (adRP)
Reference [1]?Schafer, S. et al. Nature 552, 110115 (2017)

Answering the increasing demand for novel fully human antibodies in immunotherapy, German biotech pioneer YUMAB GmbH accelerates drug discovery and development with a comprehensive and versatile technology platform.