Merck's Innovation Center

Merck KGaA is acquiring British biotech company Silence Therapeutics for $1.3 billion. The main value driver is an siRNA candidate for polycythemia vera. But the research platform and Berlin site are also part of the package. The deal is another sign that RNA interference is moving beyond a specialist technology into the broader pharmaceutical business. With a premium of 82% over the 30-day volume-weighted average share price, Merck is setting hearts racing in the siRNA community.

IDT Biologika

Helping biopharmaceutical innovators build scalable, manufacturable, and commercially viable processes from the start.

Thomas Thestrup

Following Fresenius’ launch of a €200 million healthcare venture fund in July, we invited Thomas Thestrup, managing director of Fresenius Ventures, to share his perspective in the Autumn issue of European Biotechnology. His argument: Europe has the innovation and the corporate investment expertise to compete globally, but needs more capital from its own healthcare companies to prevent the value created by European science from moving elsewhere. Here’s what he had to say:

question mark

French biotech OSE Immunotherapeutics has reported higher one-year survival rates with two combinations of its cancer vaccine Tedopi compared with chemotherapy alone in a Phase 2 lung cancer trial. However, the results are similar to those previously achieved with Tedopi alone, raising questions about the added benefit of combination treatment.

europe map

Each month, the European Medicines Agency’s human medicines committee (CHMP) weighs in on which drugs should reach European patients — and which should not. Here are eight decisions from its October meeting worth knowing.

Nouscom employees in front of chromatography machine for purification of its viral vector based products.

Swiss biotech Nouscom has raised €120 million in an oversubscribed Series D financing to advance NOUS-209, an experimental cancer vaccine designed to prevent tumors in people with Lynch syndrome, into a global registration-enabling clinical trial. Alongside the financing, the company has released new long-term clinical data showing encouraging signs of cancer prevention.

rooster weather vane

French-Belgian biotech Osivax has reported disappointing Phase 2b results for its broad-spectrum influenza vaccine OVX836, which achieved a nonsignificant efficacy estimate of 24% against a predefined target of 50%. The company is now emphasizing a strategy to combine its candidate with existing seasonal flu vaccines.

The Leadership Edit Thumbnail European Biotechnology

Every Friday, The Leadership Edit follows people taking new roles across European biotech and what their moves may tell us about the companies they join. This week: a swift scientific leadership change at Evotec, a broader reshuffle at Sibylla and a new CEO to guide AL-S Pharma toward Phase 3.

gut stomach pain

U.K. microbiome company Microbiotica has raised £36 million (€43 million), the first close of a Series C round led by the British Business Bank, to take its ulcerative colitis drug MB310 into Phase 2.

Cell therapy

Lakefront Biotherapeutics, formerly Galapagos, has sold five preclinical CAR-T assets to Belgian startup Armed Cell Therapeutics for €8 million upfront, while India’s Mankind Pharma has agreed to acquire 70% of the buyer for €48 million.