©Pixabay.com

AbbVie has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie’s neuroscience portfolio.

Alpha-Amanitin is the toxic payloads that is linked to a targeting antibody of an ATAC. © Heidelberg Pharma AG

ADC manufacturer Heidelberg Pharma AG has negotiated a US$931m licensing and investment deal with China’s Huadong Medicine Co, Ltd.

The German inventor of alpha-amanitin antibody conjugates (ATACs) will receive an upfront payment of US$20m and milestone payments of up to US$449m related to its phase 1 multiple myeloma candidate HDP-101 and preclinical prostate cancer ATAC HDP-103, as well as royalties on sales of an undisclosed amount. However, the development partnership also covers two further candidates in early preclinical development as well as options on candidates yet to be generated, which are linked to milestone payments of a further USD 461 million. After a long period of waiting, Heidelberg Pharma has thus achieved a breakthrough in the partnering of Amanitin-coupled antibody technology.

In addition to in-licensing the pipeline, Huadong is taking a 35% or €105 million stake in Heidelberg Pharma, which is funded by dievini Holdung. Huadong will enroll Asian patients in global clinical trials to accelerate product development.

Zika virus. © ECDC

Paris-based Meletios Therapeutics SA has licenced know-how from the Institut Pasteur for the development of a new class of antivirals-

   

Picture: Harvard

Barcelona-based Integra Therapeutics appoints George Church to its Scientific Advisory Board.

The world's first cultured hamburger was presented at a news conference in London on 5 August 2013. The cultured meat product was developed by a team of scientists from Maastricht University led by Mark Post at a cost of €250,000. © World Economic Forum/Wikimedia

The European Circular Bioeconomy Fund has announced its final closing at €300m, €50m above its target.

Team. © TargED Biopharmaceuticals BV

TargED Biopharmaceuticals will use €39m from a Series A financing to bring its thrombolytic treatment to patients.

CEO Maija Itkonen at the pilot production plant. © Onego Bio Ltd.

The cellular agriculture spin-off Onego Bio Ltd has been seeded with €10m to use its Trichoderma platform to establish an animal-free egg protein production.

Moderna COVID-19 vaccine production site at Lonza in Vith, Switzerland © Lonza AG

The former mRNA start-up Moderna Inc is set to expand its commercial network in six European nations to become a gobally active vaccine company.

Picture: InDex Pharmaceuticals

InDex Pharmaceuticals needs a new COO. After ten years as Chief Operating Officer, Pernilla Sandwall will leave the Stockolm-based company at the end of April.

©CDC/ multidrug-resistant Pseudomonas aeruginosa , Illustration by Jennifer Oosthuizen

Antimicrobial resistance specialist Centauri Therapeutics Ltd has closed a £24m Series A round to identify novel therapeutic candidates using the Alphamer technology.