Entries by Thomas Gabrielczyk

Santhera’s idebenone not efficient in PPMS patients

Swiss Santhera Pharmaceuticals EU-approved LHON treatment Raxone (idebenone) has failed to show clinical efficacy in another indication: After US and EU regulators rejected an extension of market approval in Duchenne muscular dystrophy last September, an NIH-sponsored trail now showed no difference to placebo treatment in patients with primary progressive multiple sclerosis (PPMS).

Convert Pharmaceuticals SA closes €13.6m Series A round

Liège-based Convert Pharmaceuticals SA has been granted a total of €13.6m in equity and non-dilutive funding by investors Droia Oncology Ventures, Meusinvest and Spinventure, with non-dilutive support by the Walloon region and funds from the European Eurostars programme.

Bavarian Nordic and AZ combine cancer jab with durvalumab

AstraZeneca (AZ) and Bavarian Nordic (BN) combine BN’s cancer vaccine CV301 and AZ’s PD-L1 checkpoint blocker durvalumab in an investigator-sponsored trail to check synergistic effects in patients with colorectal and pancreatic cancer overexpressing CEA and MUC-1.

Bioeconomy: Bringing in the public

Everybody wants green production. Bioeconomy progress, however, must become more visible to consumers and let the civil society get involved to ensure socially robust innovation and perception, according to the BioBioSTEP project.

New Screening method for Antibiotic Discovery Pipeline

A new method that determines the mode of action underlying antimicrobial compounds could help overcome a major stumbling block in the ongoing effort to discover new antibiotics. Using it, reseachers from ETH Zurich zeroed in on compounds directed against tuberculosis. 

App design for the cellular processor

Since the earliest attempts at genetic engineering, scientists have sought to influence cell behaviour and development through the introduction of foreign genetic material. Synthetic biologists are now taking the idea to a whole new plane with app-like DNA-based software programs that turn cells into diagnostic sensors, therapeutic entities or tissue generators.

Cullinan Oncology partners with MAB Discovery

Virtual oncology company Cullinan Oncology, LLC has selecteed monoclonal antibody provider MAB Discovery GmbH (Neuried)  to develop the first candidate of a target portfolio of 8-10 novel antibody therapeutics.