Tag Archive for: RNA

BioSpring GmbH has broken found for one of the world’s largest production facilities for pharmaceutical nucleic acid-based therapeutics. The new high-tech plant will significantly expand the company’s manufacturing capacity for RNA- and DNA-based active pharmaceutical ingredients, and will support Good Manufacturing Practice (GMP)-compliant production for large-scale projects on behalf of BioSpring’s global partners.

Oslo-based Coalition for Epidemic Preparedness Innovations (CEPI) has granted  US$5m to RNA formulation specialis Ethris to support studies that demonstrate spray-dried RNA vaccines remain stable at room temperature and are suitable for mucosal delivery. 

Angelini Ventures, the corporate venture capital arm of Angelini Industries, focused on investing in early-stage companies in BioTech and Digital Health, co-leads €20m Series A funding round in Neumirna Therapeutics, accelerating next-generation RNA therapeutics for epilepsy and neurological diseases.

Swiss HAYA Therapeutics SA has inked a US$1bn biobuck deal with pharma giant Eli Lilly to discover new lncRNA targets in obesity and related metabolic conditions.

© Elsie Biotechnology

GSK takes over Elsie Biotechnologies in US$50m deal to boost its oligonucleotide-based drug platform and pipeline.

© University of Southern Denmark

A German-Danish team has discovered that a truncated version of the enzyme adenlyate cyclase 3 can be targeted to transform fat-storing white adipocytes into fat-burning brown adipocytes.

Ipsen headquarters in Paris. © Ipsen SA

Ipsen SA and RNA splicing modifier specialist Skyhawk Therapeutics Inc have entered a US$1.8bn licencing option deal in rare neurological disorders.

Neurosense Therapeutics targets Alzheimer's and Parkinson's Disease but is most advanced in ALS. © Neurosense Therapeutics Ltd

ALS specialist NeuroSense Therapeutics Ltd announces it will be collaborating with Swiss Lonza AG to identify exosome-based biomarkers to advance theranostics in neurodegeneration.

Tip of the iceberg: Investigating in hart to treat indications like Glioblastoma and Pancreatic cancer, TME Pharma is hoping for proof of therapeutic superiority and many more indications to adress (©TME Pharma NV)

TME Pharma (France/Germany) announced that the US Food and Drug Administration (FDA) has granted Fast Track designation for NOX-A12 (olaptesed pegol), TME Pharma’s CXCL12 inhibitor, in combination with radiotherapy and bevacizumab for use in the treatment of the aggressive adult brain cancer glioblastoma.

Double invest by Forbion in quite different topics: in-vivo celltherapy and neurological disorders. (courtesey Capstan Inc.; Engrail Thx)

Forbion, the European life sciences venture capital firm from The Netherlands, announced its participation in oversubscribed Series B financing in Capstan Therapeutics Inc. and Engrail Therapeutics. Both companies are located in San Diego, USA.