Tag Archive for: antibody

© Calluna Pharma, edited by BIOCOM

Forbion has spearheaded a €75m Series A financing in Norwegian biotech Calluna Pharma. The clinical-stage company resulted from the merger of Oxitope Pharma and Arxx Therapeutics.

© Gerd Altmann - pixabay

Belgian fibrosis specialist Agomab Therapeutics NV has raised US$100m to advance development of its pipeline.

Hantavirus. © CDC/Cynthia Goldsmith

An international research team headed by Pablo Guardado-Calvo at Institut Pasteur Paris has demonstrated evaluated antibody efficacy against lethal hantaviruses.

Eculizumab (Soliris) is a medication used to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica.  © Naingwaiwin/wikimedia.com

Roche AG has announced positive results from the non-blinded Phase III COMMODORE 1 and 2 trials at the EHA Hybrid Congress in Frankfurt, Germany.

Figure 1: Humanization of therapeutic antibodies has reduced their immunogenicity.

Antibodies play a vital role in the immune system by providing protection against foreign invaders, such as bacteria and viruses. Produced by B cells, antibodies are protein molecules that can be harnessed to treat cancers, autoimmune disorders, and various infectious diseases. However, the human immune system may recognize modified therapeutic antibodies as foreign substances, reducing their efficacy. To overcome this challenge, the following two processes have been developed: antibody humanization and affinity maturation.

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The charity Cancer Research UK and UCB SA collaborate on the development of two potential cures for cancer.

Abb.: Tosoh

Chromatography methods and practical tips to simplify and reduce the costs of your processes