Ebola virus. © EMA

EMA’s human medicines committee (CHMP) recommended seven medicines for approval at its October 2019 meeting.

Formation of neuronal spines in neurons from wild type mice (left) and mice with mutations in the KCC2 transporter. © M. Watanabe et al., Science Signaling (2019)

A molecular transporter is critical for the proper maturation of neurons underlying neurodevelopmental disorders.

Jeremy M. Levin

There was unparalleled surprise in New York when a powerful alliance of UN-backed asset owners announced it will drive it’s portfolio companies to carbon neutrality by 2050. This could mean a fundamental change in capital markets.

© pixabay/Gerd Altmann

AI-driven drug repurposing company Healx Ltd (Cambridge, UK) raises US$56m in a Series B financing and launches global accelerator programme for orphan diseases.
 

Besides DONIMI, 4SC AG is conducting clinical testing of domatinostat in a range of indications. © 4SC AG

The Netherlands Cancer Institute (NKI) has joined 4SC AG as a partner in conducting a multicentre study of dominatostat/checkpoint blocker combos in treatment-naive melanoma patients.

© Mogrifiy

British start-up company Mogrify Ltd (Cambridge, UK) has added US$16m from a Series A round to its US$3.7m seed financing in February 2019. Existing investor Ahren Innovation Capital led the round, with Parkwalk, 24Haymarket, and the University of Bristol Enterprise Fund III participating.

Bright field image of patient-derived organoids in culture. © S.N. Ooft and M. Mertz

A new test based on tumour organoids can predict how patients with advanced colorectal cancer respond to chemotherapy treatment.

After the departure of Peer Schatz, Thierry Bernard is taking over as interim Chief Executive Officer at QIAGEN while the molecular diagnostics company is looking for a permanent head.

Affimer. © Avacta Group plc

ADC Therapeutics SA has entered a R&D pact with Affimer developer Avacta Group plc aimed at creating and licencing Affimer drug conjugates.

John Dombrosky is taking over the helm of the newly founded Oerth Bio, a targeted protein degradation joint venture launched by Bayer and US biotech Arvinas.