© Pixabay

Médecins Sans Frontières (MSF) called on the GAVI Vaccine Alliance not to pay huge subsidies to Big Pharma companies for pneumococcal vaccine

ICT01 is an activating mAb targeting the extracellular domain of BTN3A that leads to activation and trafficking of ?9?2 T cells out of the circulation.  ICT01 has been shown to promote an anti-tumor immune response against a range of cancers in in vitro and in mouse tumor models. In primates, ICT01 rapidly occupies its target and specifically activates ?9?2 T cells with a good safety profile that supports clinical testing. © ImCheck Therapeutics SAS

T cell agonist specialist ImCheck Therapeutics will use €48m (US$53m) from a Series B financing to push clincial pipeline of antibodies activating gamma-delta T-cells.

Pierre Fabre SA and Puma Biotechnology, Inc. have broadened the geographic coverage of their license agreement on commercialisation of Nerlynx® (neratinib).

© EIB

The European Commission and the European Investment Bank (EIB) have selected ECBF Management GmbH as investment advisor for the €250m EU circular bioeconomy fund.

MALT1, which was previously linked to antigen receptor?mediated NF??B activation and lymphomas, is decisive for the expansion of glioblastoma stem?like cells (GSC). © EMBO Journal

French researchers have found MALT1 blockers not only to act on blood cancers but also to be effective as a treatment for glioblastoma. 

© Dr. Edwin P. Ewing, Jr.

Researchers have designed a limb girdle muscular dystrophy 2A gene therapy preventing cardiotoxicity of calpain3 gene transfer.

MVX-ONCO-1 Treatment Plan ©MaxiVAX

Having secured a €2.785m grant from the EU and €4.55m from a Series B round, MaxiVAX is going full steam ahead with its Phase II cancer vaccine programmes.

A microglial cell, labelled in green, contacts and attacks a myelinated axon (in red). In the presence of the pHERV-W envelope protein, this interaction leads to axonal injury. The blue structures are cell nuclei. ©: HHU / Joel Gruchot / Patrick Küry

Geneva-based GeNeuro SA announced  a new clinical study of temelimab to treat patients with multiple sclerosis in collaboration with Karolinska Institute and ASC.

John Mattick has been appointed to the Board of Directors of Oxford-based research company Arctoris Ltd.

Micrograph of hepatocellular carcinoma. Liver biopsy. Trichrome stain. © Nephron

Roche AG said on Friday that its PD-L1 blocker Tecentriq plus its VEFG blocker Avastin improved progression-free survival versus sorafinib in a pivotal study in hepatocellular carcinoma (HCC) patients.