Tip of the iceberg: Investigating in hart to treat indications like Glioblastoma and Pancreatic cancer, TME Pharma is hoping for proof of therapeutic superiority and many more indications to adress (©TME Pharma NV)

TME Pharma (France/Germany) announced that the US Food and Drug Administration (FDA) has granted Fast Track designation for NOX-A12 (olaptesed pegol), TME Pharma’s CXCL12 inhibitor, in combination with radiotherapy and bevacizumab for use in the treatment of the aggressive adult brain cancer glioblastoma.

Double invest by Forbion in quite different topics: in-vivo celltherapy and neurological disorders. (courtesey Capstan Inc.; Engrail Thx)

Forbion, the European life sciences venture capital firm from The Netherlands, announced its participation in oversubscribed Series B financing in Capstan Therapeutics Inc. and Engrail Therapeutics. Both companies are located in San Diego, USA.

At the end of February, 200 German clinical trial experts gathered in Frankfurt/Main to discuss with representatives of the German Ministry of Health, how to implement model contract clauses into a law that speeds up clinical trials and translational medicine in Germany. According Model contract clauses have been established before by stakeholders from Deutsche Hochschulmedizin, das KKS-Netzwerk, die Pharmaverbände vfa und BPI sowie der CRO-Verband BVMA. © BVMA

With a new law, the German government wants to increase the number of clinical trials conducted in Germany and make the country number one in Europe again.

IgA depostis (green) in glomeruli of humanised mice. © Patrick Gleeson, University College Cork

A bacterium of the gut microbiome seems to spark an autoimmune disease in the kidneys by leaking antigens that trigger the immune system.

Myo-satellite cells grown in Innocent Meat's serum-free growth medium. © Innocent Meat

Cultivated meat producer Innocent Meat GmbH has cashed in €3m in funding from Venture Capital Fonds MV and an anonymous business angel.

Group Ferrer is headquartered in Barcelona, Catalonia, Spain. © Ferrer

Spanish Ferrer Internacional, SA has aquired the ex-US rights to VRG50635 from Verge Genomics Inc to commercialise the oral Phase I experimental ALS treatment.

Claudia Ulbrich, MD, CEO und Prof. Thomas Thum, MD, PhD, CSO/CMO at Cardior Pharmaceuticals. © Cardior Pharmaceuticals

Novo Nordisk is set to acquire German miRNA blocker specialist Cardior Pharmaceuticals GmbH for up to €1.025bn including milestone payments.

The specialized region of the muscle where the motor neuron communicates the activation signal is at the neuromuscular junction. This is a specialized synapse between a nerve and muscle. In neuromuscular diseases there are deficits in both the motor neuron side (pre-synaptic) and on the muscle side (post-synaptic). © NDM Pharma

Researchers at NDM Pharma A/S and Aarhus University have demonstrated that their oral CIC-1 blocker NMD670 restores crosstalk between neurons and muscles in Myasthenia gravis.

In future, gene vectors for novel gene therapies will be developed and produced for clinical trials on an industrial scale by around 100 employees in the new gene therapy development centre at Roche in Penzberg, which covers around 2,500 square metres. © Roche

Basel-headquartered Roche AG has inaugurated a brand new €90m gene therapy development centre in Penzberg near Munich.

Canadian Fusion Therapeutics Inc is utilising the advantages of alpha medical isotopes to develop targeted alpha therapies. The company uses targeting molecules, such as antibodies, armed with potent alpha emitting isotopes to precisely and effectively induce cancer cell death by induction of DNA double strand breaks. © Fusion Therapeutics Inc

British pharma giant AstraZeneca has announced to acquire radio-conjugate specialist Fusion Therapeutics Inc for US$2bn upfront.