A cullin-RING ubiquitin ligase, silenced in the right hemisphere, inhibits the Lewy body-like pathology triggered by exogenous alpha-Synuclein fibrils.
© Natalia Prymaczok and Juan Gerez, Science Translat. Med. doi: 10.1126/scitranslmed.aau6722

An enzyme that clears out alpha-synuclein from neurons may counteract Parkinson’s Disease, report researchers from ETH Zürich and Novartis.

© 123rf.com/Kateryna Kon

Under a partnering ageement with CEPI, Themis Bioscience will receive $21m to push pivotal testing of MV-CHIK, its Chikungunya vaccine candidate.

© 123rf.com/kletr

A fungus that produces an insecticide can stop the spread of Anopheles mosquito, which causes malaria.

© Abacus Medicine

European pharmaceutical parallel trade company Abacus Medicine A/S has postponed its planned Initial Public Offering (IPO), due to "unfavourable market environment". 

The study authors include Charles de Bock (left), Jan Cools, Roger Habets, and Bart De Strooper.
© VIB

A Belgian-British-Australian research team has created a safer version of a therapy that combats the aggressive form of a blood cancer called acute lymphoblastic leukemia (ALL) while avoiding toxicity.

Ratio of nanomedicine accumulated or cleared in the liver (red) or delivered to the target site (green). © Curadigm

Cancer-focussed Nanobiotix SA has spun out Curadigm, which offers a platform to improve the bioavailability of nanomedicines by reducing liver and spleen toxicity and accumulation.

123rf.com/Sebastian Kaulitzki

It was a good day for Novartis: A second drug with huge selling potential has been approved for the US market. The FDA gave the go ahead for breast cancer drug Piqray (alpelisib), the first and only treatment developed specifically for patients with a PIK3CA mutation in HR+/HER2-advanced breast cancer.

© 123rf.com/ ktsdesign

The FDA has approved Novartis-subsidiary AveXis Inc’s spinal muscular atrophy (SMA) gene therapy Zolgensma (onasemnogene abeparvovec-xioi). The company wants to set the price tag at $2,125m per dose.

© pixabay.com/travelkr

At BioEquity 2019, Spanish Bioindustry Association ASEBIO has given a sneak peek into its 2018 Annual Report, that each year describes the news and trends from the Spanish Biotech Sector.

Structure model of idebenone. 123rf.com/ molekuul

Chiesi Farmaceutici has licenced commercialiation rights for LHON treatment Raxone (idebenone) from Santhera Pharmaceuticals for CHF50m (€44m) in cash plus sales milestones.