In 2018 Prof. Dr Carl Blobel (photo) and Dr. Jane Salmon reported that iRhom2 inhibition protected mice from SLE. © HSS

Autoimmunity specialist SciRhom GmbH has kicked of a first-in-class antibody development programme targeting iRhom2.

Extended-spectrum Beta-lactamase (ESBL) producing Enterobacteriaceae such as E. coli cause 26,000 drug-resistant infections per year. © CDC

A drug combo breaking antibiotic resistance of Gram-negative priority pathogens has been selected under the ENABLE programme of the Innovative Medicines Initiative (IMI).

© Bergen Bbio ASA

Bergen Bio ASA’s Axl kinase blocker bemcentinib in combination with MSD’s pembrolizumab has met the primary endpoint in a Phase II study in patients with non small cell lung cancer (NSCLC).

© Scienseed / www.scienseed.com

German researchers have designed a modified Sleeping Beauty transposase that can be used for non-viral, stable and efficient gene insertions for gene and CAR-T therapies.

NCI
Breast cancer might be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells.
At its center for advanced rapid diagnostics (CARD), Mologic  with funding from the Bill and Melinda Gates Foundation  attained the ambitious milestone of 1pg/mL sensitivity in a visually read lateral-flow device. © Mologic

Synbio specialist Sherlock Biosciences and next-generation lateral flow testing expert Mologic Ltd have joined forces to develop a no-instrument rapid testing platform detecting virtually every infectious pathogen in low resource settings.

© pixabay/Tibor Janosi Mores

German researchers have shown that a protein protects against the development of liver fibrosis by shutting down inflammatory signalling in liver stellate cells of the liver. 

Cultured myocytes. © bit bio

Cell reprogramming specialist bit bio has expanded its management with renowned experts in the field.

© BioVersys

Swiss biotech company BioVersys AG has received a €8m grant by US-based non-profit organisation CARB-X to develop novel anti-virulence antibiotics to treat severe bacterial infections.

MxA activates the inflammasome: Specks of ASC, one of inflammasome proteins (indicated by arrows), were observed in the lung epithelial cells of transgenic mice infected with the influenza A virus (IAV), which expressed ihuman MxA, but not in IAV-infected mice without human MxA (non-Tg) at day three post-infection. © Lee et al., Sci. Immunol. 4, eaau4643 (2019)

A team of Japanese and German researchers has found the protein that helps activate the inflammasome following viral invasion.