A current Nature study specifies the most competitive health biotech sectors worldwide and puts Switzerland at the top, Sweden second and the USA third. Does the new math convince?
Vetter, a globally operating CDMO, won the 2022 CMO Leadership Awards in all six core categories – quality, expertise, compatibility, capabilities, reliability and service. Vetter also achieved Champion status in the areas of quality, expertise and compatibility. The award, now in its eleventh year, was given by the leading trade press publication, Life Science Leader.
The efficacy of therapeutic antibodies is defined by their primary amino acid sequence. After discovery, antibody candidates often profit from protein engineering and sequence optimisation. Different technologies can improve the functional properties of antibodies as well as their biochemical and biophysical characteristics influencing manufacturing, process development, formulation, and other parameters of the final drug target product profile.
Biologicals have shown significant success for more complex diseases, whereas small molecule drugs have not been that effective. New biologicals are mostly highly purified proteins or antibodies, which require the development of technologies for the preparation of a large number of drug candidates with high purity and speed. A high throughput magnetic beads-based system is a game-changer for biologics discovery.
In recent years, several beneficial cell samples and microbial strains have been discovered, engineered, and studied, resulting in scientific discoveries and other technological breakthroughs such as vaccines and medicines benefitting communities all around the world. However, several medical products tend to require very low temperatures for storage, making Ultra-Low Freezers increasingly important to maintain their viability.
Data Management has been a hotbed for development and innovation, correlating primarily with
the changing digital landscape. Clinical trial management has been significantly impacted, with the
electronic data capture and GDPR-compliance-led industry now unrecognisable from the paper-document administration methods of the past. This development process extends beyond COVID-19 and has a
noticeable impact on clinical trials.
Biotechnology is a key market segment for Coherent. We provide innovative solutions for academic research, pharma discovery, translational research, clinical testing, and interventional therapeutics. We support these applications with lasers, laser engines, fibers, and fiber optic components.
In the 1990s, the first clinical IVR systems (Interactive Voice Response Systems) were developed in order to randomise patients over the phone, and later, to dispense drug and resupply sites as well.
With the rapid developments in the field of gene therapy, the use of viral vectors, especially AAV, to treat various monogenic, inherited diseases in human patients is gaining momentum. Nonetheless, there are still options to optimise the production of such vectors in mammalian cells.
This year, Merck KGaA Darmstadt, Germany has acquired AmpTec, an internationally active
contract manufacturing company (CMO) with comprehensive services for manufacturing of synthetic RNAs and mRNAs and more than 15 years of experience, with cGMP compliant manufacturing capabilities in development. This marks an exciting new chapter, where our combined expertise will allow us to offer our customers innovative technologies and products to help advance life-enhancing therapeutics.