The European biotech stock market witnessed an increase in IPO and follow-on financing volumes in 2017. According to the new BIOCOM capital market report, published in November during BIO-Europe in Berlin, more than half the money was raised on the US Nasdaq. Within Europe, Euronext is still is the most attractive location – but Stockholm is catching up.
A series of high-level conferences held in autumn and winter focused on current challenges to implementing an industrial scale bioeconomy in Europe. In November, the European Commission unveiled a new stock-take of progress in its Bioeconomy Strategy, ahead of an official revision planned in 2018. In a manifesto, stakeholders demand a holistic policy framework.
Antimicrobial resistance:?In 2017, the development of new drugs and diagnostics to combat multidrug-resistant pathogens gained momentum in Europe. Small and medium-sized companies (SMEs) successfully raised financings and grants – and some new start-ups entered the scene. To continue this trend, specific support for SMEs is needed, says the BEAM Alliance.
As Big Data analytics begin to inspire medical decisionmaking, companies and scientists have gone to war over access to data derived from patient biopsies. Cancer profiling is a seminal situation. While some companies are seeking to profit from approaches to advanced mutation analysis, researchers are vociferous in demanding open access to proprietary databases behind company firewalls.
Pharmapack 2018 Focus:?The dawning age of digital healthcare is expected to transform the pharma packaging and drug delivery sector. At the 21st edition of Pharmapack Europe (7-8 February, 2018, Paris), an expected 5000+ professionals and 400+ exhibiting companies – the industrys largest meeting ever – will discuss the latest innovations in serialisation, connected devices, and digitalised meds.
Its still under the radar of analysts. However, the vasoactive peptide adrenomedullin could become the Next Big Thing in therapy monitoring and the treatment of disorders caused by endothelial dysfunction such as acute heart failure, or septic shock. During a scientific symposium Endothelial Dysfunction – Adrenomedullin as a diagnostic and therapeutic target (19. December 2017, Berlin), 15 international medical key opinion leaders from ICU/EDs for the first time compiled clinical data from more than 10,000 patients that underscore that adrenomedullin could lead to a paradigm shift in the diagnosis, monitoring and treatment of disorders linked to endothelial dysfunction.
The renewable energy sector is ramping up in a major way, but a host of infrastructure issues still need to be solved. One is that supply at times now outstrips demand, but theres no way to store excess power. Turning it into an easy-to-store, energy-rich source like methane could solve the problem. A pivotal aspect of power-to-gas technology harnesses some tiny helpers usually found in some of the most extreme regions on the planet.
Considering the high development costs of medications and the time invested before a drug goes from discovery to market, it is critical to develop not only a solid drug development strategy, but a contemporary manufacturing strategy as well. A parallel development strategy could be one possible approach.
For years, neurologists have hunted for the source of cell toxicity that drives neurodegeneration and cognitive decline in Alzheimers disease. An Indian researcher at the University of Zurich might now have solved the mystery. Its not hidden in amyloid plaques, as researchers previously believed, but in the microglia, the brains innate immune system, which triggers loss of synaptic junctions resulting in loss of cognitive functions.
In the past, the role of customised and tailored formulations have been largely underestimated in the field of biopharmaceutical product development. An advanced formulation strategy can strongly improve the product, leading to significant customer benefits. The growing and increasingly competitive biopharmaceutical market requires individual solutions, particularly for better product stability and prolonged shelf life.