Oxford-based immuno-oncology play Adaptimmune has been obliged by the FDA to alter the trial design of a Phase I/II study in patients with MRCLS. A partial clinical hold was lifted now.

Belgian and German researchers have presented a new imaging tool that can track immune cells invading the brain in the initial stages of multiple sclerosis (MS). 

Compassionate use is a treatment option that allows the use of an unauthorised medicine.

PromoKine’s new Cell Proliferation Assays are fast and sensitive and EdU-based.

Despite declining numbers of IPOs, financing rounds and licensing deals, the European biotech sector presented itself optimistic and self-confident during BIO-Europe in Cologne. The three-days partnering event again see a record number of participants. 

Cologne-based biotech Ayoxxa Biosystems GmbH announces that Rodney Turner has assumed duties as the interim CEO. Prior CEO Andreas Schmidt has stepped down.

Pharmatio GmbH, already established in the monitoring and site liaison of clinical trials, has restructured its services. With Clinical Trial Liaison, the sponsors of clinical trials can ensure the patient recruitment and effectiveness of their clinical trials. The Clinical Trial Task Force masters difficult or unforeseen challenges in clinical trials, and High Quality Monitoring ensures that Pharmatio ensures all-­time inspection readiness of clinical trial sites.

Dutch immuno-oncology company Merus has appointed John Crowley its Chief Financial Officer. Former CFO Shelley Margetson has been elevated to Chief Operating Officer. 

French cellular immunotherapy company TxCell has hired ex-Novartis Lab Head Li Zhou to lead its CAR-Treg programmes. Zhou was appointed Vice President Cell Engineering in October.

After AstraZeneca removed its NSCLC drug osimertinib from the German market following a benefit assessment of German health technology assessor G-BA negatively impacting price negotiations, the German oncologist association DGHO accuses the G-BA not to act in the best interest of lung cancer patients.