Its still under the radar of analysts. However, the vasoactive peptide adrenomedullin could become the Next Big Thing in therapy monitoring and the treatment of disorders caused by endothelial dysfunction such as acute heart failure, or septic shock. During a scientific symposium Endothelial Dysfunction – Adrenomedullin as a diagnostic and therapeutic target (19. December 2017, Berlin), 15 international medical key opinion leaders from ICU/EDs for the first time compiled clinical data from more than 10,000 patients that underscore that adrenomedullin could lead to a paradigm shift in the diagnosis, monitoring and treatment of disorders linked to endothelial dysfunction.
Whats up in 2018?
Latest NewsThere is a lot of reports on technologies that have already entered the mainstream and will continue to grow in 2018 such as T-cell receptor targeted cancer, autoimmune and gene therapies. European Biotechnology Magazine takes a look on what really is new and has the potential to change current medical paradigms.
KOLs see paradigm shift in the diagnosis and treatment of common disesases
BackgroundIts still under the radar of analysts. However, the vasoactive peptide adrenomedullin could become the Next Big Thing in therapy monitoring and the treatment of disorders caused by endothelial dysfunction such as acute heart failure, or septic shock. During a scientific symposium Endothelial Dysfunction – Adrenomedullin as a diagnostic and therapeutic target (19. December 2017, Berlin), 15 international medical key opinion leaders from ICU/EDs for the first time compiled clinical data from more than 10,000 patients that underscore that adrenomedullin could lead to a paradigm shift in the diagnosis, monitoring and treatment of disorders linked to endothelial dysfunction.
Cancer senescence: licence to kill
Latest NewsTherapy-induced senescence (TIS), a lasting chemotherapy-evoked proliferative arrest of tumor cells, has been thought to be irreversible. As it turns out now, it makes tumour cells, which survive, more aggressive and worsens prognosis.
Sheets of eye cells improve retina repair
Latest NewsScientists have generated sheets of human eye cells arranged on a biological scaffold, which they used to successfully treat vision disorders in rats.
Roche does not have to pay US$685m fine
Latest NewsThe European Commission has closed its very first infringement procedure under the Penalty Regulation. During an inspection at Roches UK headquarters in 2012 the British MHRA found data on 80,000 not properly reported adverse events of approved Roche meds, 15,161 of which included deaths.
A new fund from the north
Latest NewsHadean Ventures announced the launch of Hadean Capital I, a fund that will invest up to € 100 m in life science companies, with a particular focus on the Nordic region.
CHMP recommends EU approval of seven medicines
Latest NewsThe European Medicines Agencys Committee for Medicinal Products for Human Use (CHMP) recommended seven medicines for approval at its December 2017 meeting, including two orphan medicines, and one biosimilar.
Sally Ann Forsyth to join SBC
AppointmentsStevenage Bioscience Catalyst (SBC) has announced that Dr. Sally Ann Forsyth is set to join the company as CEO in March 2018.
reMYND in €350m diabetes deal with Novo
Latest NewsBelgian reMYND N.V. has out licenced worldwide commercialisation rights for its small molecule programme ReS39 in diabetes to Novo Nordisk A/S. The drug impedes death of insulin-producing beta cells by preventing the formation of cytotoxic islet amyloid polypeptide (IAPP) aggregates.
TB urine test outperforms standard of care
Latest NewsA new, non-invasive tuberculosis urine test prevents common disadvantages of the standard tuberculin skin test: Measuring lipoarabinomannan glycan from M. tuberculosis, it detects the active disease in early stage and does not interfere with co-infections or weakened immune system.