Up to now, researchers believed that lung remodeling follows an auto­immune inflammation triggered by components of the extracellular matrix. In August, British scientists provided a more accurate view of the processes in the lung tissue, opening up a way to optimise failed mid-stage clinical candidates.

In mid-October, the European Investment Bank (EIB), the Kreditanstalt für Wiederaufbau (KfW) and the Agence Française de Developpement launched a five-year €2bn initiative called "Clean Oceans", which is dedicated to sustainable solutions set to reduce the amount of 8 million tons of plastic that are littered into the oceans every year. About 90% of the plastic waste and the resulting microplastic particles come from Asia, Africa and the Middle East. © KfW

The European Parliament has approved measures that could lead to a ban of the top 10 single use plastic products that contribute to marine littering by 2021.
    

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Zelluna Immunotherapy has announced the appointment of Geir Christian Melen as chief financial officer (CFO).

Olav Zilian

Big Pharma’s interest in R&D on anti-infectives declined when other areas like oncology began offering higher returns. A few biotechs mirror pharma (Basilea, Idorsia and Polyphor), but could stay hidden gems.

© Innate Pharma SA

AstraZeneca plc has extended its immunoncology pipeline by an extension of its partnership with French Innate Pharma SA.

Intestinal villi. © fololia.com/fololiaxrender

French Enterome SA has added a second licence agreement with Takeda to its deal portfolio, projecting possible payments of US$640m.

The European Medicines Agency delays the EU approval of Nivolumab/Ipilimumab in NSCLC and greenlights four biotherapeutics to be marketed in the EU.

Plantics NV won the EFIB PitchFest. © BIOCOM AG

Industrial biotech innovations, presented in at the 11th EFIB in Toulouse, could become the key enabler set to save our planet if supported appropriately.

Simplified presentation of freeze-drying cycle development including the boundaries of DoE. Picture: Vetter Pharma-Fertigung GmbH & Co. KG

As the global demand for injectables grows, so does the demand for innovative delivery systems. For lyophilised forms, dual-chamber systems offer advantages. They have been on the market since the mid-1980s, mainly for emergency or chronic medication. The systems have been developed for the convenience of the patients/caregivers, but they also offer benefits for the pharma/biotech companies in regards to low residual volume and increased API yield.

© ColiN00B / Pixabay

Oxford Nanopore Technologies has impressed Amgen with its genetic sequencing technology. The US biopharma major has invested £50m in the Oxford-based company.