Human cell chip predicts chemotherapy effects Roche and US company Hesperos Inc have used human cancer and organ cells, placed in a 5-chamber microfluidic chip, to predict chemotherapy safety and efficacy preclinically. more ➔
IL-10R-deficient macrophages trigger IBDResearchers from Israel and the UK have identified how the cytokine IL-23 triggers inflammatory bowel syndrome (IBD), which affects 1.6 million patients annually in the US alone. more ➔
Breakthrough in liquid biopsy German and US researchers have developed a diagnostic technique capable to detect one single circulating tumour cell in one litre of blood. more ➔
ADC Therapeutics raise $76m in Series E expansionSwiss antibody drug conjugate developer ADC Therapeutics SA raised $76m, bringing the total gross proceeds to $276 million in its Series E financing. more ➔
Janssen and Genmab in licence option dealJanssen Biotech Inc has inked a licence option contract with Genmab A/S on its next-generation anti CD38 antibody HexaBody®-CD38 and HexaBody platform technology. more ➔
Evotec bags US$23.8m to fight tuberculosis The Bill & Melinda Gates Foundation has granted Evotec SE $23.8m to identify the best drug combos to fight tuberculosis. more ➔
How lungs trigger innate lymphoid cell dynamicsThe cells’ surrounding structures play an important role as cues from the immune system in guiding their motility and behaviour, researchers from the UK and the US report. more ➔
Researchers find clue to Parkinson’s gene therapy An enzyme that clears out alpha-synuclein from neurons may counteract Parkinson’s Disease, report researchers from ETH Zürich and Novartis. more ➔
Chikungunya vaccine developer Themis bags $21mUnder a partnering ageement with CEPI, Themis Bioscience will receive $21m to push pivotal testing of MV-CHIK, its Chikungunya vaccine candidate. more ➔
Genetically modified fungus stops malaria mosquitoes A fungus that produces an insecticide can stop the spread of Anopheles mosquito, which causes malaria. more ➔