Single B cell screening is a powerful and efficient strategy for generating antigen-specific monoclonal antibodies (mAbs).

Break free from the long reaction times, high costs, and method complexity of manual proteomic sample preparation with the Thermo Scientific™ AccelerOme™ automated sample preparation platform. With factory-supplied reagents and kits, and step-by-step onscreen instructions, high reproducibility and confident results are delivered for both label-free and tandem mass tag (TMT) multiplexing strategies with minimal effort. The AccelerOme platform is optimized to fit into the Thermo Scientific™ Orbitrap™ mass spectrometer ecosystem, streamlining the entire workflow from sample preparation to data processing.

An anti-idiotypic anti­body (anti-ID Ab) can recognise and bind to the idiotypic center of another antibody. Anti-idiotype antibodies are widely used in therapeutic drug development, such as immunogenicity assessments, pharmacokinetic/pharmacodynamics (PK/PD) studies, and vaccine development.

The EchoLUTION Tissue DNA Kit from BioEcho was developed to isolate high-quality DNA in a short time, even from difficult-to-extract samples such as muscle and adipose tissue. Due to the significantly shorter lysis and reduced number of steps, the entire workflow is three to ten times faster than conventional methods that follow the bind-wash-elute principle.

A rapid antigen test provides a fast and reliable indication of the presence of the SARS-CoV-2 virus, the causative agent of Covid-19. A positive result of an antigen test is reliable, whereas a negative result does not completely rule out infection with the SARS-CoV-2 virus. The success of rapid tests is therefore limited by the sensitivity of the antibodies used.

Leading the way with the industry’s largest portfolio of CE-IVD labeled flow cytometry reagents in the market, Beckman Coulter Life Sciences announces that it has received a EU Quality Management System Certificate under the new In Vitro Diagnostic Medical Devices Regulation (IVDR) for more than 200 flow cytometry reagents developed and manufactured at their Marseille, France facility.

Given Omicron Varinat’s potential higher rate of transmissibility, Fapon Biotech has successfully introduced SARS-CoV-2 Omicron Variant Neutralizing Antibody Titer Testing Solution (ELISA) to effectively evaluate the immune evasiveness and vaccine effectiveness on Omicron varian.

ANTIGENS Seasonal flu is a common infectious disease of the respiratory tract caused by influenza virus. There are four types of influenza virus, influenza type A, B, C, and D. The A and B types are of most interest to the medical community because they are the culprits for seasonal epidemics. Occasionally, influenza A, like the A/California/04/09 (H1N1) and A/Hong Kong/1/1968 (H3N2), can even cause global pandemics.

The HyPeak™ Chromatography System provides a complete, single-use solution for chromatographic purification—a principal unit operation in downstream bioprocessing of recombinant proteins such as monocolonal antibodies and viral vector production. Pre-engineered system options and modular-flow kit designs allow for selection of tools and technology suitable for a broad range of applications. The HyPeak Chromatography System can be used for multiple chromatography steps and, combined with the automation package, provides the platform necessary for consistent, high-performing purification