Cell cycle, © science.memebase.com

UK researchers have identified a highly conserved target structure that can be directed to rush dividing cancer cells into premature division and cell death.

Profiling of mutations in genes of the RAS family, including KRAS, offers selection of potential responders to targeted therapies,  © Sysmex Inostics

Merck KGaA has expanded its portfolio of blood-based RAS diagnostics for use in patient stratification. After kicking off testing with Sysmex Inostics’ CE-marked OncoBEAM RAS CRC liquid biopsy assay last year, the German drug maker welcomed the launch of a second blood-based test to detect KRAS mutations in patients with colorectal cancer (CRC): Biocartis’  Idylla ctKRAS Mutation Assay.

TiGenix researchers in the lab, © TiGenix

Euronext Brussels-noted adipose stem cell player TiGenix NV wants to offer 2.75 million American Depositary Shares (ADS) in an IPO at Nasdaq Global Market representing 55 million of its ordinary shares which had went up from  €0.91 yesterday to €0.96 (10.a.m.).

Strucure model of NI 0101, © Novimmune

Roche’s US subsidiary Genentech has acquired an exclusive option to commercialise Novimmune’s TLR4 antibody NI-0101, the very first personalised approach to treat rheumatoid arthritis. The compound has already proved safety and drugability in a Phase I dose escalation trail.

Viennese Apeptico Forschung und Entwicklung GmbH and Milan-based Mediolanum Farmaceutici S.p.A. have signed a research & development cooperation and license agreement for Apeptico’s compound solnatide.

BIOCOM

For the second time, biotech communication start-up Labiotech hosted its event LBRefresh, this year in Paris, France. Participants enjoyed panel discussions, a start-up battle and intimate fireside chats…

Waldemar Kütt, European Commission, at 11th EUBP conference in Berlin, © European Bioplastics

EU consumers have minor knowledge on bioplastics but unrealistically high expectations that can not be fulfilled, researchers said at 11th European Bioplastics Conference in Berlin.

French Carbios has presented a process that depolymerises one of the most common non-recycled plastics polluting the oceans. 

Human Interferon Alpha, © Nevit Dilmen / NCBI

French immunotherapy expert Neovacs has teamed up with CDMO 3P Biopharmaceuticals for the manufacture of interferon alpha with recently licensed technology.

© Kymab

UK-based biopharma group Kymab has brought a new backer from China on board. With the help from ORI Healthcare Fund, Kymab secured a US$100m Series C financing.