Ebola virus. © EMA

EMA’s human medicines committee (CHMP) recommended seven medicines for approval at its October 2019 meeting.

Formation of neuronal spines in neurons from wild type mice (left) and mice with mutations in the KCC2 transporter. © M. Watanabe et al., Science Signaling (2019)

A molecular transporter is critical for the proper maturation of neurons underlying neurodevelopmental disorders.

© pixabay/Gerd Altmann

AI-driven drug repurposing company Healx Ltd (Cambridge, UK) raises US$56m in a Series B financing and launches global accelerator programme for orphan diseases.
 

Besides DONIMI, 4SC AG is conducting clinical testing of domatinostat in a range of indications. © 4SC AG

The Netherlands Cancer Institute (NKI) has joined 4SC AG as a partner in conducting a multicentre study of dominatostat/checkpoint blocker combos in treatment-naive melanoma patients.

© Mogrifiy

British start-up company Mogrify Ltd (Cambridge, UK) has added US$16m from a Series A round to its US$3.7m seed financing in February 2019. Existing investor Ahren Innovation Capital led the round, with Parkwalk, 24Haymarket, and the University of Bristol Enterprise Fund III participating.

Bright field image of patient-derived organoids in culture. © S.N. Ooft and M. Mertz

A new test based on tumour organoids can predict how patients with advanced colorectal cancer respond to chemotherapy treatment.

Affimer. © Avacta Group plc

ADC Therapeutics SA has entered a R&D pact with Affimer developer Avacta Group plc aimed at creating and licencing Affimer drug conjugates.

© Pixabay/Clker-Free-Vector-Images

Licencing bluebird bio’s Inc know-how and technology in one-time gene therapies, Novo Nordisk A/S tries to get a foothold in the emerging haemophilia A gene therapy market.

Evotec SE has expanded its drug discovery customer base with US women’s health specialist Celmatix Inc.

QIAGEN and Illumina join forces in the next-gen sequencing-based IVD testing and companion diagnostics market announcing a 15-year collaboration.