@ UniQure

Dutch gene therapy company UniQure has launched a US$200m stock offering on Nasdaq.

Picture: 123rf.com/ belchonock

Polpharma Biologics SA has partnered up with Novartis subsidiary Sandoz AG to market a natalizumab biosimilar. As part of the global commercialization agreement, Polpharma Biologics will be responsible for the development, manufacturing and supply of the collaboration biosimilar, which is currently in Phase III clinical development for the treatment of relapsing-remitting multiple sclerosis (RRMS).

© Zealand Pharma

German pharma company Boehringer Ingelheim said the phase II trial for candidate drug BI456906 is expected to be initiated in late 2019 triggering a €20m milestone payment to Zealand Pharma A/S.

Alexndre Mebazza's presenting results at ESC Congress 2019 in Paris. @ sphingotec GmbH

Results presented at European Society of  Cardiology Congress 2019 demonstrate a new disease mechanism predicting acute organ dysfunction in heart failure patients.

A US-EU research team has found that a class of compounds that promote tumour cell death can also limit autoimmunity.

Lab at immatics. © Immatics Biotechnologies

Celgene will pay $75m upfront to get an option on three cancer programmes developed by Immatics Biotechnologies.

Uniprotein. © Unibio Group

Danish microbiology specialist Unibio International plc had completed a US$15m financing round led by West Hill Capital.

Freenome's CEO Gabriel Otte at this year's Future of Individualized Medicine 2019 conference. © Scripps Research Institute

US company Freenome will use its multiomics platform to develop response biomarkers to ADC Therapeutics’ Phase II antibody drug conjugate (ADC) ADCT-402.

© GSK

GlaxoSmithKline plc announced belantamab mafodotin (GSK2857916) met the primary endpoint of overall response rate (ORR) in a pivotal Phase II trial in treatment-refractive multiple myeloma.

Steffen Brünle (right) and Jörg Standfuss at the apparatus they use to separate proteins from each other. For their study, the researchers modified insect cells to produce a human protein. To extract this from the cell, the cell was destroyed, and then the protein, whose structure the researchers have now elucidated, was separated with the help of this apparatus. © Paul Scherrer Institute/Markus Fischer

Researchers from Paul Scherrer Institute in Villingen, Switzerland, and Hoffmann La-Roche AG report in Cell they have solved the structure of a target relevant in metastasis.