ADC structure. In ATACs the cytotoxic payload is alpha-amanitin. © International Journal of Molecular Sciences, doi: 10.3390/ijms17040561
JO  - s

Magenta Therapeutics has exercised the option to licence Heidelberg Pharma AG’s anti-CD45-Antibody Targeted Amanitin Conjugate (ATAC).

Geralt / Pixabay

Swiss-German biotech Vaximm is teaming up with Tokyo-based AI specialist NEC to advance personalised neoantigen cancer vaccines.

Geralt / Pixabay

Expedeon has sold its immunology and proteomics business activities to global life sciences company Abcam. Abcam is paying €120m in cash for the business.

In 2018 Prof. Dr Carl Blobel (photo) and Dr. Jane Salmon reported that iRhom2 inhibition protected mice from SLE. © HSS

Autoimmunity specialist SciRhom GmbH has kicked of a first-in-class antibody development programme targeting iRhom2.

Extended-spectrum Beta-lactamase (ESBL) producing Enterobacteriaceae such as E. coli cause 26,000 drug-resistant infections per year. © CDC

A drug combo breaking antibiotic resistance of Gram-negative priority pathogens has been selected under the ENABLE programme of the Innovative Medicines Initiative (IMI).

© Bergen Bbio ASA

Bergen Bio ASA’s Axl kinase blocker bemcentinib in combination with MSD’s pembrolizumab has met the primary endpoint in a Phase II study in patients with non small cell lung cancer (NSCLC).

© Scienseed / www.scienseed.com

German researchers have designed a modified Sleeping Beauty transposase that can be used for non-viral, stable and efficient gene insertions for gene and CAR-T therapies.

NCI
Breast cancer might be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells.
At its center for advanced rapid diagnostics (CARD), Mologic  with funding from the Bill and Melinda Gates Foundation  attained the ambitious milestone of 1pg/mL sensitivity in a visually read lateral-flow device. © Mologic

Synbio specialist Sherlock Biosciences and next-generation lateral flow testing expert Mologic Ltd have joined forces to develop a no-instrument rapid testing platform detecting virtually every infectious pathogen in low resource settings.

© pixabay/Tibor Janosi Mores

German researchers have shown that a protein protects against the development of liver fibrosis by shutting down inflammatory signalling in liver stellate cells of the liver.