B.1.1.7 variant associated with higher mortality
The B.1.1.7 variant of SARS-CoV-2, which was first identified in the UK, may be associated with an increased risk of death, a Nature study suggests.
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Entries by Thomas Gabrielczyk
Roche in take-over deal with GenMark Diagnostics
Roche to acquire GenMark Diagnostics, Inc., to access platform to test for broad range of pathogens with one patient sample.
Media hype on Denmark’s decision to halt AZD1222 vaccination
While media reports suggest AstraZeneca’s COVID-19 jab might have caused blot clots, the EMA didn’t confirm a causal relationship.
Roche Phase III study misses COVID-19 endpoint
Swiss Roche AG has missed the primary endpoint in the REMDACTA trial in patients with severe COVID-19 pneumonia.
Vaccine production in Africa: an urgent priority
Africa produces less than 1% of the human vaccines it uses. To effectively respond in time of outbreaks and pandemics, Africa must expand its vaccine development and production capabilities to cater for its growing population. Successfully establishing such an industry at scale is a multifaceted endeavour to create an enabling environment. This article highlights key factors and considerations for establishing local vaccine manufacturing.
A very “cool” topic in the parmaceutical industry
The current debates regarding vaccine production and logistics have also made it clear even to the layman: Pharmaceutical production depends on cold. Temperatures below -80?°C are just as common as the requirement to freeze precursors such as blood plasma within a specified time period. Refrigeration specialists with pharmaceutical know-how are in demand for these challenging tasks.
BioPhero A/S raises US$17m in Series A funding
Danish sustainable crop protection company, BioPhero AS, has raised $17m in Series A funding led by DCVC Bio.
PCR-test reveals risk of genotoxity of genome editing
German researchers have presented a new method to assess on-target and off-target effects of CRISPR-Cas nucleases or TALENs.
EMA starts rolling review for Sputnik V vaccine
EMA’s human medicines committee has started a rolling review of Sputnik V, a COVID-19 vaccine developed by Russia’s Gamaleya National Centre of Epidemiology and Microbiology.
Novel RNA extraction method speeds up COVID-19 PCR tests
Although innovative biotechnologies are developed continuously, the method of nucleic acid extraction stayed unchanged for several decades. The classical bind-wash-elute approach seemed sufficient, but the COVID-19 pandemic uncovered the need for a new technique to be able to process multiple samples fast and in parallel. BioEcho developed a completely new technology, which simplifies and speeds up the process of RNA extraction dramatically.