Group Ferrer is headquartered in Barcelona, Catalonia, Spain. © Ferrer

Spanish Ferrer Internacional, SA has aquired the ex-US rights to VRG50635 from Verge Genomics Inc to commercialise the oral Phase I experimental ALS treatment.

Ion Arocena; General Manager Asebio; © Asebio

Born with the aim of harmonising the application, evaluation, and supervision process of clinical trials conducted in EU countries, there is much room for improvement for the Clinical Trial Information System CTIS, particularly with regard to SMEs and translational researchers.

Claudia Ulbrich, MD, CEO und Prof. Thomas Thum, MD, PhD, CSO/CMO at Cardior Pharmaceuticals. © Cardior Pharmaceuticals

Novo Nordisk is set to acquire German miRNA blocker specialist Cardior Pharmaceuticals GmbH for up to €1.025bn including milestone payments.

The specialized region of the muscle where the motor neuron communicates the activation signal is at the neuromuscular junction. This is a specialized synapse between a nerve and muscle. In neuromuscular diseases there are deficits in both the motor neuron side (pre-synaptic) and on the muscle side (post-synaptic). © NDM Pharma

Researchers at NDM Pharma A/S and Aarhus University have demonstrated that their oral CIC-1 blocker NMD670 restores crosstalk between neurons and muscles in Myasthenia gravis.

In future, gene vectors for novel gene therapies will be developed and produced for clinical trials on an industrial scale by around 100 employees in the new gene therapy development centre at Roche in Penzberg, which covers around 2,500 square metres. © Roche

Basel-headquartered Roche AG has inaugurated a brand new €90m gene therapy development centre in Penzberg near Munich.

Canadian Fusion Therapeutics Inc is utilising the advantages of alpha medical isotopes to develop targeted alpha therapies. The company uses targeting molecules, such as antibodies, armed with potent alpha emitting isotopes to precisely and effectively induce cancer cell death by induction of DNA double strand breaks. © Fusion Therapeutics Inc

British pharma giant AstraZeneca has announced to acquire radio-conjugate specialist Fusion Therapeutics Inc for US$2bn upfront.

Primary astrocyte cells. © Dr Eva Latorre, Harries lab/Senisca Ltd

Exeter-based university spin-out Senisca Ltd has added £3.7m seed money to a £1.1m not dilutive funding to advance its pipeline of drugs targetting RNA splicing dysregulation.

Despite the recent stock market rally and declining volatility, IPOs are rather rare in many industrialised countries –not least for seasonal reasons. The main reason for this, however, is the aggressive monetary policy of the central banks, with more than ten interest rate hikes in both Europe and the US. 

Manufacturing process of n.c.a. Lutetium-177, ©ITM

Radiopharmaceutical Therapy (RPT) is offering several advantages over existing therapeutic strategies. The highly sought-after therapeutics require a sophisticated supply chain, as radioisotopes have short half-lives and must be delivered to patients with extreme speed and efficiency. ITM rises to this challenge as one of the largest global providers and developers of medical radioisotopes for this novel therapy.

Figure 1: Example of a process landscape; © Richter-Helm BioLogics GmbH & Co.KG

The biotech and pharma branch is growing steadily. Many companies have full order books for the next few years and expect growth. This is the basis for new investments in assets and infrastructure. These growing structures often expose vulnerabilities and challenges for the business. Therefore, companies need to increase the stability and efficiency of their processes.