Picture © Sygnature Discovery

Sygnature Discovery, thas appointed Dr Bill Marathias as Vice President of Business Development for the US to assist with the company’s international growth plans.

An artist's illustration of a seizure discharge recorded from a slice of human epileptic brain tissue with electrodes. © E. Dossi et al., Science Translational Medicine (2018)

French researchers have found a key driver of chronic epilepsy. 

eb_online_appointment_juuel.jpg

Bavarian Nordic A/S today announced the appointment of Henrik Juuel to the position of Executive Vice President and Chief Financial Officer. Mr. Juuel is currently the CFO of Orexo AB.

F-Star claims to be the first company that can create bispecifics that incorporate a binding site on the constant Fc region of the antibody. © EPvantage

Brain disease specialist Denali Therapeutics will buy all outstanding shares in British F-Star Gamma Ltd from F-Star instead licencing bispecific antibody candidates that can cross the blood-brain barrier (BBB) co-developed under an agreement dating back to 2016.

Picture © Cellectis

Nordic Nanovector ASA today announces that Rainer Boehm, MD was elected as a member of its Board of Directors at the company’s Annual General Meeting on 30 May 2018.

Roche announced that atezolimumab plus chemotherapy met its co-primary endpoints of overall survival (OS) and progression-free survival (PFS) as first-line treatment of stage IV nonsquamous non small cell lung cancer (NSCLC).

Picture © Nouscom

Nouscom, an immuno-oncology company developing off-the-shelf and personalized neoantigen-based genetic cancer vaccines, announced today the appointment of Adrian Woolfson M.D., Ph.D. as Chief Medical Officer (CMO).

Principle of CAR-T cell therapy. © Memorial Sloan Kettering Cancer Center

Interleukin 1 (IL-1) blockers may prevent serious adverse events triggered by CAR-T cell therapies, according to two independent studies.

CD38 antibodies attacking multiple myeloma cells. © Sumit Sharma/Pininterest

Following reports of an increase in mortality in a study that combined Genmab’s anti-CD38 daratumumab with a PD-L1 blocker, Genmab’s partner Janssen has stopped a study combining daratumumab with its PD1 blocker JNJ-63723283 in multiple myeloma.

Besides its RAS cancer vaccine, Targovax is testing an oncolytic virus + checkpoint inhibitor in cancer. © Targovax ASA

Targovax ASA’s cancer immunotherapy TG01 significantly prolonged 2-year overall survival of patients with resected pancreatic cancer versus standard therapy. Targovax’ shares were up 16% on Thursday evening.