Lefamulin blocks the peptidyl transferase site of the ribosome. © Nabriva Therapeutics plc
Nabriva Therapeutics plc has got the go from the FDA to market its pleuromutilin antibiotic Xenleta (lefamulin), a protein synthesis blocker with new mode-of-action to treat community-acquired bacterial pneumonia.
Araris Biotech CEO Philipp Spycher. © Paul Scherrer Institute/Mahir Dzambegovic

Zurich-based ADC maker Araris Biotech AG announced the closing of an oversubscribed seed financing round of CHF2.5m with Redalpine, Schroder Adveq and VI Partners contibuting.

Iteos Therapeutics SA, a privately-held biotechnology company developing novel cancer immunotherapies, last week announced the appointment of Matthew Call as its Chief Operating Officer. Matthew will also be responsible for business development.

Picture: Henrik Larsson/stock.adobe.com

Although it has only been shown to provide partial protection,  the first-ever malaria vaccine is in testing in Africa – and there are many more hopefuls in the pipeline. Will we soon eradicate one of the most deadly pathogens in human history?

The FDA has given the go-ahead to PharmaMar’s proposal to file for accelerated approval its New Drug Application (NDA) for lurbinectedin monotherapy for the treatment of second-line small-cell lung cancer.

Picture: Vetter

Manufacturers respond to stricter regulations with novel approaches.

Aerial image Karolinska Institutet Campus Flemingsberg, 2019. Photographer: barabild.se

Researchers at Karolinska Institutet have discovered a new sensory receptor organ that is able to detect painful mechanical damage, such as pricks and impacts.

Mitosis. ©  By Mysid - Vectorized in CorelDraw by Mysid / https://commons.wikimedia.org/w/index.php?curid=1414818

British researchers have found out what’s going wrong with chromosome segregation in some cancers. 

© Pharming
Pharming NV has paid €17.9m upfront to Novartis AG for an exclusive license to CDZ173, a late stage drug for the treatment of APDS
Group of mesenchymal (green) stem cells migrating in a tooth to further regenerate tissues.
© Media and Communications | University of Plymouth

Researchers have discovered that crosstalk of a newly discovered stem cell population with quiescent stem cells may help repair teeth in the future.