© Zealand Pharma

German pharma company Boehringer Ingelheim said the phase II trial for candidate drug BI456906 is expected to be initiated in late 2019 triggering a €20m milestone payment to Zealand Pharma A/S.

Alexndre Mebazza's presenting results at ESC Congress 2019 in Paris. @ sphingotec GmbH

Results presented at European Society of  Cardiology Congress 2019 demonstrate a new disease mechanism predicting acute organ dysfunction in heart failure patients.

A US-EU research team has found that a class of compounds that promote tumour cell death can also limit autoimmunity.

Plant Breeding Project. 4 DNA preparations each (purified with EchoLUTION Plant DNA 96 Kit, see flowchart left) from 8 different vegetable or fruit leaf punches were spectrophotometrically analyzed. All samples were detected with high yield and optimal purity ratios.

BioEcho develops single-spin and 96-well kits for the isolation of DNA from different starting materials. Their proprietary EchoLUTION single-step technology avoids the use of inhibitory process reagents while using dedicated efficient lysis reagents for e.g. different plant tissues. In contrast to common bind-wash-elute procedures, the process does not require washing steps. The inhibitor-free DNA enables lowered time-to-result in enzyme-dependent genomic analyses such as PCR or NGS.

Lab at immatics. © Immatics Biotechnologies

Celgene will pay $75m upfront to get an option on three cancer programmes developed by Immatics Biotechnologies.

Uniprotein. © Unibio Group

Danish microbiology specialist Unibio International plc had completed a US$15m financing round led by West Hill Capital.

Freenome's CEO Gabriel Otte at this year's Future of Individualized Medicine 2019 conference. © Scripps Research Institute

US company Freenome will use its multiomics platform to develop response biomarkers to ADC Therapeutics’ Phase II antibody drug conjugate (ADC) ADCT-402.

© GSK

GlaxoSmithKline plc announced belantamab mafodotin (GSK2857916) met the primary endpoint of overall response rate (ORR) in a pivotal Phase II trial in treatment-refractive multiple myeloma.

Steffen Brünle (right) and Jörg Standfuss at the apparatus they use to separate proteins from each other. For their study, the researchers modified insect cells to produce a human protein. To extract this from the cell, the cell was destroyed, and then the protein, whose structure the researchers have now elucidated, was separated with the help of this apparatus. © Paul Scherrer Institute/Markus Fischer

Researchers from Paul Scherrer Institute in Villingen, Switzerland, and Hoffmann La-Roche AG report in Cell they have solved the structure of a target relevant in metastasis.

Red blood cell. © pixabay

An antibody therapy that targets red blood cells (RBCs) unexpectedly showed anti-inflammatory effects and rapidly reversed rheumatoid arthritis and prevented lung injury in mouse models.