CAR T cells attacking cancer. © Prasad S. Adusumilli, MD, FACS/Memorial Sloan Kettering Cancer Center

Drug puts CAR T activity on hold

German researchers have found a way to curb the activity of CAR T cells, even while keeping their cancer-fighting properties intact.

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IN Carta image analysis software segmentation masks and heat maps of the SSc FMT markers and intensity features. Assay plates are imaged using the IN Cell Analyzer 6000 and IN Carta image analysis software from GE. Settings used: Nuclei detection (Fast), Cell detection (Robust), and Organelles-Cells-Fibers. Our first assumption was to look at intensity related measures like intensity or density. This did not yield a very strong pattern for our control wells vs the samples and negative controls. Picture: GE Healthcare

Biotech company Galapagos improves high-content screening (HCS) in scleroderma with IN Carta Phenoglyphs image analysis

Galapagos’s mission is to develop first-in-class medicines based on the discovery of novel targets. Using human primary healthy andpatient cells, the company discovers which proteins play a key role in diseases such as rheumatoid arthritis, inflammatory bowel disease, and fibrosis.

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Frédéric Tangy, founder of Oncovita and director of the viral genomics and vaccination unit at Institut Pasteur

License deal in oncolytic virotherapies

Oncovita has been granted the exclusive license to an immuno-oncolytic measles virus platform developed by the Institut Pasteur. Based on the technology, the Paris-based biotech plans to develop cancer therapies.

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Helena Strigård becomes CEO of Swedenbio

Swedenbio’s Board has appointed Helena Strigård as the new CEO. Strigård will take up the position on September 1 and replace Jonas Ekstrand,

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Teckro Expands Leadership Team

Teckro today announced five significant appointments to its leadership team. The hires follow Teckro’s Series C funding announcement in February, featuring investment from major US venture capital firms. To date, Teckro has raised $43 million.

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© BI

Boehringer Ingelheim and Yuhan Corp. in US$870m NASH deal

Boehringer Ingelheim has licenced a preclinical fusion protein from Korean Yuhan Corp. that activates both GLP-1R and FGF21R to treat Nonalcoholic Steatohepatitis (NASH). Boehringer Ingelheim will pay $40m upfront and in near-term payments to acquire the commercialisation rights to the compound. Under the agreement, Yuhan Corp. is eligible to receive up to USD 830 million in potential milestone payments plus tiered royalties on future net sales.
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Interpretation of a mammogram by the radiologist. © Service communication HNFC

Smart bra set to detect breast cancer

A French-Swiss research team is developing a smart bra for detecting breast cancer more accessible than through mammography.

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Picture: European Parliament

Trilogue put lights on green for Horizon Europe

The European Council, the European Parliament, and the outgoing European Commission have agreed upon the priorities and structure of Horizon Europe (2021 to 2027), the next seven-year research and innovation programme of the European Union. This autumn, they will decide on the Parliament’s proposal to increase its budget from €100bn to €120bn.

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GARDP wants five AMR breakers by 2025

GARDP has called up the global community to develop and deliver five new treatments that break antimicrobial resistance (AMR) by 2025.

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Jean-Paul Kress, Picture: Quantum Genomics

New CEO at Morphosys

Germany-based MorphoSys AG announced that its Supervisory Board has today appointed Jean-Paul Kress, M.D., as its new Chief Executive Officer. The appointment will take effect on September 1, 2019.

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