Swiss big pharma Roche has agreed to license ZW209, an experimental cancer immunotherapy from Vancouver-based Zymeworks, for $55 million upfront and up to $758 million more in conditional payments, plus royalties on future sales. The agreement returns Roche to DLL3, a lung cancer target it previously pursued with a different antibody.
Every Friday, The Leadership Edit follows people taking new roles across European biotech and what their moves may tell us about the companies they join. This week: a hearing-loss specialist adds clinical leadership, a radiopharmaceutical developer strengthens drug discovery and a gene-editing company changes finance chief.
Switzerland’s Roche has discontinued RG6540, an experimental off-the-shelf CAR-T therapy targeting the CD19 and CD20 proteins, less than two years after agreeing to acquire its developer, Poseida Therapeutics, for up to $1.5 billion (€1.3 billion). Roche has not explained the reasons for the decision, but CEO Thomas Schinecker told reporters that the acquisition had yielded other CD19/CD20 candidates he considers superior.
Italy’s Menarini Group will pay Maryland biotech Georgiamune $45 million (€40 million) in upfront and near-term payments, in a deal worth up to $1.1 billion (€1.0 billion) plus royalties, for worldwide rights to an oral cancer immunotherapy that has yet to enter human trials.
Swedish private equity firm EQT wants to acquire diagnostics specialist Qiagen for €10.8 billion, or €46.50 per share. The company’s leadership unanimously supports the sale. Completion is planned for mid-2027 if more than 50% of shareholders agree.
An experimental oral drug for early Alzheimer’s disease has produced positive Phase 1 results, including shifts in spinal-fluid markers of brain immune activity and neuronal stress in older volunteers toward levels seen in younger people, Danish biotech Muna Therapeutics reported. The drug, MNA-001, was also well tolerated, with no serious adverse events or adverse-event-related discontinuations reported.
Icelandic biotech Arctic Therapeutics has raised $21.5 million (€19.1 million) in an oversubscribed round to take two drug candidates for autoimmune disease toward the clinic.
At the IZB in Martinsried, Invitris is developing a cell-free platform to turn digital sequences into proteins, antibodies and phages within hours. CEO Patrick Grossmann explains why AI is shifting the bottleneck from drug design to manufacturing, how Phactory™ addresses phage production and why microgravity could open new possibilities.
Beyond the main headlines, European biotech kept moving this week. This edition of Meanwhile in Biotech covers cancer vaccine follow-up, changes to kidney and obesity trials, and two developments in AI-enabled drug discovery. Here are six updates worth catching up on.
British rare disease specialist Ambrose Healthcare has acquired Dutch biotech AM-Pharma for up to €161 million, adding an enzyme replacement therapy to its pipeline and a development base in Utrecht.