Denmark’s Genmab said adding its bispecific antibody petosemtamab to MSD’s Keytruda (pembrolizumab) cut the risk of death by 50% versus Keytruda alone in a Phase 3 trial in first-line, PD-L1-positive recurrent or metastatic head and neck cancer. The interim result is the first randomized evidence for the lead asset of Genmab’s $8 billion takeover of Dutch biotech Merus last year.
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A Phase III win for Moderna and Merck’s personalized mRNA cancer vaccine has reignited investor enthusiasm for mRNA — and put BioNTech back in the spotlight. But the data are more important than the stock rally: for the first time, a personalized mRNA cancer therapy has produced positive Phase III data in a major indication.



Moderna