German 4SC AG’s epigenetic cancer drug resminostat is back. What seemed to be a flop after Phase II failure has being transformed into a success story of personalised medicine. By accurate data analysis 4SC’s partner Yakult Honsha identified a subgroup in which the drug significantly improved outcomes for patients with hepatocellular carcinoma (HCC).

The surprising election of Donald Trump as the next US President led to a spectacular comeback of biotech shares. The long-term prospects depend on Trump’s healthcare strategy and the (much-desired) return of generalist funds.

Oxford-based Intrexion-subsidiary Oxitec plans to release male GM mosquitoes that produce nonviable offspring in India, in order to limit the spread of dengue and chikungunya fevers transmitted by Aedes aegyptii.

Two biotech CEOs have been selected by the European Commission for the High Level Group. The EU think tank will provide strategic input to Horizon 2020 and a €2.5bn fund to support innovation by 2020 in order to boost disruptive technologies and to address gaps in in the current innovation support landscape. 

While German Nasdaq company Affimed (AFMD) had an accumulated loss of over €100m, an annual development cost of about €38m for its Tandab pipeline, and an income of only about €8m from collaborations at the end of 2015, the company is trying to bulk up its funds through a public offering of common stock. 

Promega-founder William Linton has been elected as a member of the Supervisory Board of lab supplier Eppendorf AG.

Belgian start-up company Octimet Oncology NV has secured €11.3m in a series A financing round. The funds will be used to develop two MET kinase blockers to treat solid tumours.

Drug screening expert Evotec AG and Ontario-based MaRS Innovation have launched the joint venture company Fibrocor Therapeutics LP to tackle fibrosis, an unmet medical need and multi-billion US dollars market. 

London-based brain health company Ixico has hired Giulio Cerroni as its new Chief Executive Officer. Cerroni replaced co-founder Derek Hill, who will remain on the board and serve as executive director going forward. 

Scientists at EPFL have developed a technique that can be a game-changer for genetics by making the characterisation of DNA-binding proteins much faster, more accurate, and efficient.