Eduarado Bravo, Picture: Tigenix

Tigenix NV, a biopharmaceutical company focused on exploiting the anti-inflammatory properties of allogeneic stem cells, today announces that Eduardo Bravo will depart the board of directors and his role as CEO of Tigenix effective as of June 15, 2018.

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Celonic AG has pursued an ambitious expansion strategy in mammalian cell line contract manufacturing to establish Phase III and commercial supply by mid-2019. A new GMP facility in Heidelberg was acquired, and capacity is also being expanded at the headquarters in Basel. European Biotechnology spoke with Franzpeter Bracht, COO of Celonic, about Celonic’s strategy.

Øystein Soug, CEO of Targovax. © Targovax ASA

Despite a 6-month improvement of 2-year-overall survival in pancreatic cancer patients, Norwegian cancer immunotherapy specialist Targovax ASA will terminate development of TG01 in this indication. Instead, development of RAS neoantigen-targeting cancer vaccines will be pushed in colorectal cancer.

Picture © Eppendorf

Fibra-Cel Disks are an advanced, solid support material for the efficient growth of mammalian and insect cells in bioreactors. They are devised to improve the cultivation of anchorage-dependent as well as suspension cells. Fibra-Cel Disks can be used also for perfusion cell culture with the Eppendorf packed-bed impeller – available for glass, stainless steel, and single-use bioreactors.

This April, Autolus Therapeutics and Miltenyi Biotec inked a long-term agreement on the supply and support of Miltenyi Biotec's CliniMACS Prodigy instruments, reagents and disposables for the manufacture of Autolus' programmed T cell therapies. © Miltenyi Biotec

British T cell player, Autolus Therapeutics Ltd. wants to go NASDAQ selling 7.8 million American Depositary Shares (ADSs) at  at least US-$15, totaling in US$117m. Through a greenshoe option, Autolus want to offer additional 1,171,875 ADS at the IPO price. 

Press conference by Jyrki Katainen, Vice-President of the EC in charge of Jobs, Growth, Investment and Competitiveness, and Commissioner Moedas on the 2012-2027 European Research and Innovation programmes. © Audiovisual Service of the EC

EU Commissioners Jyrki Katainen and Carlos Moedas proposed a budget increase of 25% for the next  European Research and Innovation programme Horizon Europe (2021-27) vs Horizon 2020. However MEPs said that the new moonshot research section EIC is underfunded. Furthermore, the current funding quote of 11% was too low compared to other international excellence programmes.

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Josh Muntner has been appointed Chief Financial Officer of Mesoblast. He will be based in New York.

© Biogen

Alkermes plc (Dublin) received a US$50m milestone payment from Biogen after review of preliminary Phase III gastrointestinal tolerability data of Alkermes’ relapsing-remitting multiple sclerosis candidate diroximel fumarate (BIIB098).

© Hoopkia Biotech AG

Austrian arenaviral vector technology specialist Hookipa Biotech AG (Vienna, Austria) has licenced its TheraT and Vaxwave technologies exclusively to Gilead Sciences Inc. to develop and globally commercialise vaccines against the human immunodeficiency virus (HIV) and the hepatitis B virus (HBV).

image © Walgreens

PureTech Health plc announced today that its affiliate, Gelesis, has appointed Harry Leider, MD, MBA, former Chief Medical Officer and Group Vice President of Walgreens, as Chief Medical Officer.