In March 2021, Dr Jane Robertson will take over the position of Chief Medical Officer at Redx Pharma Plc in Alderley Park.

© NIAID

Boehringer Ingelheim announced the start of Phase II studies of its oral TRPC6 blocker code-named BI 764198 in patients hospitalised for COVID-19.

© CANDOR Bioscience GmbH

AP-Protector® is a long-term stabilizer for alkaline phosphatase (AP) coupled to antibodies or Neutravidin/Streptavidin.

3P Biopharmaceuticals expanded its manufacturing and process development capacities in 2017 launching a new manufacturing site in Noain that even allows commercial production of biologics and cell therapies.

British SpyBiotech has outsourced GMP manufacturing of its VLP vaccine platform to Navarra-based 3P Biopharmaceuticals.

Antibody manufacturing at Bioinvent. © Bioinvent AB

Swedish BioInvent AB has licensed its anti-Fc?RllB antibody BI-1206 for $95m to CASI Pharmaceuticals for distribtion in the Greater China region

   

HPV, © NIH

Transgene SA has reported positive results of an exploratory Phase Ib/II study in HPV-16-positive cancers combining its cancer vaccine TG4001 with Merck KgaA’s PD-L1 blocker avelumab.

Medical Cannabis – Last year, the European Cannabis Association was launched as industry interest group, but than the novel coronavirus pandemic changed everything. European Biotechnology spoke with Rainer Krüger, one of the ECA founders, how the virus changed the schedule and strategy to establish a science-based regulation for medicinal cannabis.

Antiviral drugs are hoped to eliminate the novel Coronavirus right from the beginning of infection and thus ameliorate severe courses of COVID-19. Besides nucleoside analogues, blockers of the highly conserved viral main protease or antibodies that target the spike protein are under clinical development. © Roche

Roche AG has paid US$350 in cash to co.develop and market Atea Pharmaceutical’s oral direct-acting antiviral, AT-527, to limit proliferation of SARS-CoV-2.

Araris' linker technology enables site-specific payload attachment to a specific amino acid (Q295) within the IgG-Fc framework. When a payload is attached to this site, the antibody still maintains nearly identical performance (e.g. pharmacokinetics and effector functions) to the unconjugated, original antibody. Furthermore, the linker-payload is connected to the antibody through a very strong peptide bond resulting in exceptional stability in the blood stream and thus minimal adverse effects. © Araris Biotech AG

New ADC company Araris Biotech has got backing by Pureos Bioventures and co-investors in a CHF15.2m seed round to develop a new class of antibody drug conjugates.
 
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96-well EchoLUTION ultra-fast RNA/DNA extraction - flowchart. Just one centrifugation step is required to obtain highly pure inhibitor-free nucleic acid (left and right). If extracting viral RNA for, e. g., SARS-CoV-2 tests, the processing time is reduced to only 2 minutes (left). For purification of genomic DNA from various materials, the time varies from 10 to 30 minutes (right). Bioecho recently received the award „innovative through research. Picture: BioEcho

BioEcho develops single-spin and 96/384-well kits based on the patent pending single-step EchoLUTION nucleic acid extraction process. Highly superior to the commonly used silica-based solutions (bind-wash-elute), the isolated inhibitor-free RNA/DNA is detected with increased sensitivity. Furthermore, the whole procedure is up to 20-fold faster: Washing steps are not required, saving time, costs and plastic waste. Due to the expertise of its founders and employees, BioEcho also uses its know-how to support diagnostic or pharma companies with specialized scientific knowledge. Especially in times like these, BioEcho helps to accelerate accurate tests on certain RNA/DNA viruses such as SARS-CoV-2.