Portugal-based Exogenus Therapeutics will lead a five-year, €13 million Horizon Europe project to advance its osteoarthritis candidate EXO-101 into clinical testing.
Switzerland-based Idorsia has launched a new pivotal Phase 3 trial of lucerastat in Fabry disease, targeting kidney deposits after its first late-stage study failed to reduce nerve pain. The company also signed a development and commercialization agreement with Japan’s Nxera Pharma, which will help fund the program.
Switzerland-based Atlas Bio has emerged from stealth with $12.5 million in funding to develop AI simulations that predict drug responses, with the ambition of replacing parts of clinical development and animal testing.
Swiss pharma group Ferring Pharmaceuticals has agreed to acquire New York-based Gameto for up to $1.3825 billion (€1.24 billion), gaining a cell-based approach designed to shorten the hormone treatment needed for in vitro fertilization (IVF) and egg freezing.
Beyond the main headlines, European biotech kept moving this week. This edition of Meanwhile in Biotech covers an Alzheimer’s program dropped from Novartis’ pipeline, a Swiss biotech’s Nasdaq ambitions, a hepatitis B approval and new directions in RNA medicines and neuroscience.
The European Society for Medical Oncology (ESMO) Congress is one of the biggest events on the cancer research calendar, where clinical results can reshape treatment decisions and drug developers’ prospects. This year, Immatics presented new data for its PRAME-targeting therapies, BioNTech expanded the evidence for its bispecific antibody pumitamig, and AstraZeneca reported survival gains across several cancers. Here’s our roundup of the most important announcements from European biopharma.
Germany-based cancer immunotherapy specialist Immatics presented updated clinical data for two PRAME-targeted drug candidates at the ESMO Congress 2026 in Madrid. Particularly striking is the survival signal for the bispecific T-cell engager IMA402: In a subgroup of patients with advanced melanoma and high PRAME expression, 91% were still alive after one year. Median overall survival had not yet been reached at the time of analysis.
Sweden’s Spago Nanomedical will ask shareholders on Nov. 19 to approve delisting from Nasdaq First North, arguing that its listing obstructs financing on acceptable terms for Phase 2a development of its Tumorad radiopharmaceutical in head and neck cancer.
Inspired by technology and insights gleaned from cancer research, Europe is leading the quest for a new generation of therapies in immunology and inflammation. Immunotherapy has revolutionised cancer therapy and become standard of care in many areas of oncology but it has also begun to change outcomes in inflammatory and autoimmune diseases.
Denmark’s Genmab has reported that its antibody-drug conjugate rinatabart sesutecan (Rina-S) reduced the risk of progression or death by 71% and the risk of death by 57%, compared with conventional chemotherapy in a 584-patient Phase 3 trial of platinum-resistant ovarian cancer. It has also released updated colorectal cancer data for its bispecific antibody petosemtamab.