Center for Sustainable Materials Clermont-Ferrand by Michelin ©Michelin

French dairy giant Danone, engineering materials group Michelin, US start-up DMC Biotechnologies and Crédit Agricole Centre France have joined forces to create the Biotech Open Platform as  precision fermentation centre.

Rat microglia grown in tissue culture in green, along with nerve fiber processes shown in red. © Gary Shaw - wikipedia.org

German researchers have tracked down the causes for central nervous system side effects of cancer immunotherapies and blocked them in small animal models.

Misfolded protein accumulation and evidence of ISR activationis present in multiple neurological conditions. © BMS and Hetz et al, Nat Rev – Neur 2017

Evotec SE has reached a predefined milestone worth €20m in the CRO’s partnership with Bristol Myers Squibb (BMS).

CEO Dr Peter Sondermann © Tacalyx GmbH

Glycan target specialist Tacalyx GmbH expands its seed financing to €14m to advance its anti-TACA cancer therapies.

PAS amd CD3 staining of renal tissue at day 10 (scale bars, 10 μm). © Leon U. B. Enk

Researchers at University Hospital Hamburg-Eppendorf have laid the foundation to screen for molecules that shift Th17 cells from proinflammatory or immune-dampening mode.
 

© Elsie Biotechnology

GSK takes over Elsie Biotechnologies in US$50m deal to boost its oligonucleotide-based drug platform and pipeline.

Lu 177-dotatate (pink and orange) binds to somatostatin receptors (green) on neuroendocrine tumor cells (blue) and kills the cells through the release of radioactive  particles.@ NCI. Credit: Adapted from Frontiers in Oncology. January 2019. Front. Oncol. doi: 10.3389/fonc.201800663

ITM Isotope Technologies Munich SE has raised €188m ito boost radiopharma pipeline, contract manufacturing cpacity, and launch ITM-11.

Quantro used thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM seq), an orthogonal-chemistry-based RNA sequencing technology that detects 4-thiouridine (s4U) incorporation in RNA species at single-nucleotide resolution, to measure RNA-polymerase-II-dependent gene expression dynamics. © QUANTRO Therapeutics GmbH

Viennese biotech QUANTRO Therapeutics identifies small molecule targeting an onkogenic transcription factor in Boehringer Ingelheim collab.

DefiniGEN's hepatocyte NAFLD cell_model. © DefiniGEN' Ltd

DefiniGEN Ltd., and Atelerix Ltd. have successfully shipped in vitro liver models from the UK to the US without freezing them thus preventing cell damage and loss-of function.

Approvals for RNA-based drugs in the past decade. © IQVIA

With the opening of a production centRE for RNA vaccines and therapeutics, German CDMO Wacker Biotech is expanding its expertise in the field of RNA active ingredients.