A capsule by design to delivery whatever is to deliver, that´s the promise of new start-up Exvolvo @Exvolvo Biosciences

NLC Health Ventures (Amsterdam, The Netherlands), in partnership with Verily, the precision health technology daughter company of Alphabet/Google, will launch Exolvo Biosciences, a pioneering biotech company providing the next-generation solution for biologic drug delivery as oral administration.

In Valneva´s laboratories ©Valneva SE

Valneva announces Health Canada approval of the world’s first chikungunya vaccine, IXCHIQ®.

Cystein as specific target for payloads in Tubulis' ADC plattform ©Tubulis GmbH

Tubulis doses first patient in phase 1/2a trial investigating ADC candidate TUB-040 in ovarian cancer and lung adenocarcinoma (NSCLC). TUB-040 is a NaPi2b-targeting Exatecan ADC based on Tubulis’ proprietary linker technology with better biophysical properties that demonstrated effective and durable responses in a range of preclinical models.  

©Pixabay.com/Priampatel4

The BIOSECURE Act of the United States could affect more than 120 US biopharmaceutical drugs partnered with Chinese companies ‘of concern’, as named in the bill. Of these, approximately half are in clinical trials (phases I to III) and a third are in early preclinical and discovery stages, according to GlobalData, the analytics company.

Center for Sustainable Materials Clermont-Ferrand by Michelin ©Michelin

French dairy giant Danone, engineering materials group Michelin, US start-up DMC Biotechnologies and Crédit Agricole Centre France have joined forces to create the Biotech Open Platform as  precision fermentation centre.

Rat microglia grown in tissue culture in green, along with nerve fiber processes shown in red. © Gary Shaw - wikipedia.org

German researchers have tracked down the causes for central nervous system side effects of cancer immunotherapies and blocked them in small animal models.

Misfolded protein accumulation and evidence of ISR activationis present in multiple neurological conditions. © BMS and Hetz et al, Nat Rev – Neur 2017

Evotec SE has reached a predefined milestone worth €20m in the CRO’s partnership with Bristol Myers Squibb (BMS).

CEO Dr Peter Sondermann © Tacalyx GmbH

Glycan target specialist Tacalyx GmbH expands its seed financing to €14m to advance its anti-TACA cancer therapies.

PAS amd CD3 staining of renal tissue at day 10 (scale bars, 10 μm). © Leon U. B. Enk

Researchers at University Hospital Hamburg-Eppendorf have laid the foundation to screen for molecules that shift Th17 cells from proinflammatory or immune-dampening mode.
 

© Elsie Biotechnology

GSK takes over Elsie Biotechnologies in US$50m deal to boost its oligonucleotide-based drug platform and pipeline.