Italy’s Menarini Group will pay Maryland biotech Georgiamune $45 million (€40 million) in upfront and near-term payments, in a deal worth up to $1.1 billion (€1.0 billion) plus royalties, for worldwide rights to an oral cancer immunotherapy that has yet to enter human trials.
French biotech OSE Immunotherapeutics has reported positive topline Phase II data for its cancer vaccine Tedopi in recurrent ovarian cancer, but the clinical signal is most clearly seen in combination with MSD’s anti-PD-1 antibody Keytruda.
German researchers have tracked down the causes for central nervous system side effects of cancer immunotherapies and blocked them in small animal models.