Genmab logo, © Genmab A/S

Danish Genmab A/S’ anti-CD38 antibody daratumumab has met the endpoint of progression-free survival in an interim analysis of Genmab’s pivotal Phase III study aimed at receiving FDA approval as first-line therapy in multiple myeloma. 

Merck Ventures has joined the Series A investor syndicate of the British immuno-oncology specialist Macrophage Pharma Ltd.

Scientists at Swedish Karolinska Institute have identified a factor that supports growth of midbrain dopaminergic (mDA) neurons, the nerve cells that degenerate during of Parkinson’s disease.

Peptides that trigger immune system dampening Treg responses in liver stem cells use nanocarriers as transport vesicles, © Topas Therapeutics GmbH

Evotec’s immunology spin-out Topas Therapeutics has inked a multi-year R&D collaboration with pharma major Eli Lilly. The initial focus of research, which will be financed by Eli Lilly, is on identification of  antigens that specifically induce a T regulatory cell response in inflammatory and auto-immune disorders.

Medivir's headquarters in Stockholm, © lakemedelsvarlden.se

Medivir AB has exclusively licenced Greater China development and commercialisation rights of its preclinical candidate drug MIV-802 to Chinese drug developer Ascletis Bioscience Co. Ltd.

A slide of tissue sections to be stained and incubated with antibodies to see which proteins are expressed, © Nature, doi:10.1038/509645a

Using a national supercomputer, Swedish researchers have analysed how protein expression of the 315 known cancer genes translates into cancer overall survival. 

martin-laqua.jpg

Finnish Metsä Group has started its mill for bio-based products. The €1.2bn investment’s production capacity is 1.3 million tonnes of softwood pulp a year.

sascha-karberg.jpg

UK-headquartered immunodiagnostics specialist Oxford Immunotec Global plc’s  share value slipped by $1.31 to $16.02 after the company raised US-$40.125m on Monday in an public offering of 2.5 million ordinary shares at Nasdaq underwritten by BTIG LLC.

uta-mommert.jpg

German CellAct GmbH has cashed in US$250m (€212m) from Mundipharma in a licence deal for CAP7.1, a Phase II drug to treat the rare biliary tract cancer. 

Adrezizumab modulates Adrenomedullin
activity and, preclinically, improved vascular integrity and sepsis survival, © Adrenomed AG

Germany is the first country that has granted full approval to Adrenomed to conduct a Phase II study with the monoclonal antibody adrecizumab in patients with early septic shock. Within the ADR-02 study, 300 patients will be enrolled in Germany, Belgium, France and the Netherlands for proof of safety and efficacy.