Steatohepatitis © Nephron/commons.wikimedia.org/w/index.php?curid=7747223

NorthSea Therapeutics BV has raised US$40m to provide proof-of-concept of its NASH drug icosabutate.

© 4SC AG

4SC AG and Merck KgaA  have signed a supply agreement to start clinical tests of Merck’s checkpoint blocker avelumab plus 4SC’s HDAC I blocker domatinostat.

© CDC

Mutabilis and IBT Vaccines have successfully bagged US$12m from the Novo Holdings REPAIR Impact Fund.
 

Postulated mechanisms of mortality in sepsis. © Sphingotec GmbH

Critical care experts have presented data supporting the thesis that three specific pathways are the cause for about 90% of sepsis mortality.

P. aeruginosa. © CDC

Antabio SAS has got a US-$4.4m tranche from CARB-X to advance preclinical development of its P. aeruginosa treatment in Cystic Fibrosis patients

© Pixabay/Hans Braxmeier

Swedish and Danish researchers have created a hydrogel that kills various types of bacteria and reduces inflammation in mice and pigs with infected wounds.

© Oxford Biodynamics

The technology of Oxford-based Oxford Biodynamics (OBD) promises insights into why immunotherapies only work in some patients but not in all. A major US pharma company now wants to validate OBD’s epigenetic biomarker discovery and development platform causing a share price gain of 15%.

© Beata Dudová/Pexels

Paris-based European venture capital company Truffle Capital closed its €250m BioMedTech fund – celebrating its company building approach.

Mode of action of CB-103
© Cellestia

Basel-based biopharma company Cellestia Biotech AG has successfully closed a Series B financing round, raising a total of CHF 20 million.

Sphingotec headquarters, © Sphingotec GmbH

Data from 1,200 heart failure patients demonstrate that high discharge levels of the biomarker bio-ADM® (bioactive Adrenomedullin) indicate residual congestion in heart failure patients.