© Dr Graham Beards at en.wikipedia, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=25206097

The EU has made poor progress combatting antimicrobial resistance, a report from the European Court of Auditors (ECA) warns. Innovators need to be supported, urges the BEAM Alliance.
 
 

© Cellectis SA

Researchers at French-US allogeneic CAR-T cell developer Cellectis SA have designed an engineered CAR-T cell that secretes IL-12 upon contact with tumour cells.

Magenta Therapeutics has exercised the option to licence Heidelberg Pharma AG’s anti-CD45-Antibody Targeted Amanitin Conjugate (ATAC).

Geralt / Pixabay

Swiss-German biotech Vaximm is teaming up with Tokyo-based AI specialist NEC to advance personalised neoantigen cancer vaccines.

Geralt / Pixabay

Expedeon has sold its immunology and proteomics business activities to global life sciences company Abcam. Abcam is paying €120m in cash for the business.

In 2018 Prof. Dr Carl Blobel (photo) and Dr. Jane Salmon reported that iRhom2 inhibition protected mice from SLE. © HSS

Autoimmunity specialist SciRhom GmbH has kicked of a first-in-class antibody development programme targeting iRhom2.

Extended-spectrum Beta-lactamase (ESBL) producing Enterobacteriaceae such as E. coli cause 26,000 drug-resistant infections per year. © CDC

A drug combo breaking antibiotic resistance of Gram-negative priority pathogens has been selected under the ENABLE programme of the Innovative Medicines Initiative (IMI).

© Bergen Bbio ASA

Bergen Bio ASA’s Axl kinase blocker bemcentinib in combination with MSD’s pembrolizumab has met the primary endpoint in a Phase II study in patients with non small cell lung cancer (NSCLC).

© Scienseed / www.scienseed.com

German researchers have designed a modified Sleeping Beauty transposase that can be used for non-viral, stable and efficient gene insertions for gene and CAR-T therapies.

NCI
Breast cancer might be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells.