Group of mesenchymal (green) stem cells migrating in a tooth to further regenerate tissues. © Media and Communications | University of Plymouth

New stem cell population may help repair teeth

Researchers have discovered that crosstalk of a newly discovered stem cell population with quiescent stem cells may help repair teeth in the future.

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iPSCs derived from somatic cells through a novel reprogramming method. © UCLA Broad Stem Cell Research Center/Plath Lab

Bayer bags iPSC specialist BlueRock Therapeutics

Bayer has widened its pipeline in neurology, cardiology, and immunology by acquiring induced pluripotent stem cell specialist BlueRock Therapeutics.

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Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The exact mechanism of ctDNA release is unknown. Once ctDNA is isolated, it can be sequenced for mutational analysis. © Creative commons licence, RachelJuneWong

Liquid biopsy identifies residual breast cancer

Using a platform tailored to patients’ specific cancer mutations, British and US researchers for the first time detected residual disease in breast cancer patients.

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Waste carbon streams as resources for Lanzatech's process. © Lanzatech

Novo Holdings puts $72m in Lanzatech

Novo Holdings A/S (Novo Holdings) invests $72m in LanzaTech to support development of the company’s sustainable fuels and chemicals platform
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With the "BigStitcher" software you can reconstruct a sample and then rotate and turn it virtually, get an overview of the big picture or zoom into individual structures. This works both as a user, as illustrated here, and as an algorithm that analyzes the data and cannot load the entire image into RAM. Neurons expressing a specific gene are marked in green. Such data now make it possible for the first time to systematically characterize differences at the single-cell level between normal and genetically modified mice and to draw conclusions about potential behavioral changes that may result. © Preibisch Lab / Treier Lab, MDC

Google maps for tumours and organs

German researchers have developed a software that allows to manage and correct the huge amount of data generated by 3D reconstruction of tumours or organs using light sheet microscopy.
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Vaccinia virus. © wikipedia/commons PHIL

Transgene’s licenced oncolytic virus fails in Phase III

SillaJen, the licensor for French immunoncology specialist Transgene SA, has stopped enrolment into the Phase III Phocus trial after an Independent Data Review Comittee predicted the study endpoint won’t be met.

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Wellington Partner's Managing Partner Rainer Strohmenger. © UroMems

Wellington Partners launch €210m Life Sciences fund

Wellington Partners has closed its largest Life Sciences Fund ever. The VC specialist outperformed its intial target of raising €120m to €150m and closed at €210m.

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© pixabay/julientromeur

Alizé Pharma 3 bags largest EU financing so far

Venture Captital specialist LSP led a €67m Series A financing in peptide developer Alizé Pharma 3.

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Microscopic images of either wild type (left) or mutant (right) HeLa cells treated with TNF-alpha. © P.E. Morton et al., Science Signaling (2019)

Better TNF? receptor blockers on the horizon

Two research teams have unraveled the complex dynamics of TNF? receptor signaling and have identified compounds that may be safer than current treatments.

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Agrosavfe's agrocapsules are made by coupling stable camelid agrobodies to microcapsules containing active substances to protect seeds, crops and produce from weeds, pests and diseases. © AgroSavfe NV

AgroSavfe raises €35m in Series C financing

Plant protection specialist AgroSavfe will use the funds of a €35m Series C financing to push the development, registration and commercial scale production of its biofungicides and bio-insecticide.

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