Entries by Joachim Eeckhout

Sanofi joins the mRNA vaccine patent wars

Sanofi has sued Pfizer and Moderna, alleging that their COVID-19 and respiratory syncytial virus (RSV) vaccines infringe patents covering the delivery of messenger RNA using lipid nanoparticles it acquired through the acquisition of Translate Bio in 2021.

AstraZeneca and Ionis miss in key ATTR-CM trial

AstraZeneca and Ionis have suffered a major late-stage setback after Wainua/Wainzua (eplontersen) failed to hit the primary endpoint in a phase 3 trial in transthyretin-mediated amyloid cardiomyopathy (ATTR-CM), denting hopes that the RNA-targeted therapy could compete in one of cardiology’s fastest-growing rare disease markets.