Excess of Bacteroides species in the microbiome are an indicator for enhanced responsivess to CTLA4 checkpoint inhibitors such as BMS' ipilimumab.

French gut microbiome analysis specialist Enterome Bioscience SA and therapeutic nutrition company Nestlé Health Science have formed a 50:50 joint venture aimed at developing microbiome-based diagnostics for certain common diseases. 

© Bayer AG

Bayer has always been extremely supportive of the new Unitary Patent System (UPS) and has been one of the driving forces behind it within the German industry. However, the company will not be putting its full portfolio through the UPS and the Unified Patent Court (UPC).

© Bio-M Biotech Cluster Development GmbH

As part of a €5bn investment by 2025, the Free State of Bavaria will kick off two ambitious digital medicine projects next year, government officials said at the Forum Science & Health.  

VIPs at Roche's ceremony (from left to right): 
Digital infrastructure minister Alexander Dobrindt, Dr. Ursula Redeker, spokesperson of the Executive Board at Roche Diagnostics, Dr. Christoph Franz, Chairman of the Administrative Board, Roche AG, Ilse Aigner, Bavarian Minister of Economic Affairs; and Media, Energy and Technology, Dr. Hagen Pfundner, CEO, Roche Pharma AG, Germany, Jens Spahn, State Secretary at the Federal Ministry of Finance, © Roche Diagnostics

At the opening ceremony for R&D, training and production buildings at Roche Penzberg, the Pharma giant said that Foundation Medicine (FMI) will establish a digital oncology service at the site offering oncologists across Europe decision support in personalised medicine.

Belgian diagnostics company Biocartis Group NV and Singpore’s A*STAR ETPL have kicked off development of a multimodal breast cancer assay designed to guide therapy selection in personalised medicine.

© 4SC AG

Small molecule cancer drug developer 4SC AG (Planegg-Martinsried, Germany) has completed a capital increase fueling development of its clinical programmes for resminostat, 4SC-202 and 4SC-208

German biotech company Biontech AG has published positive clinical results for its individualised cancer vaccine Ivac mutanome in patients with late-stage melanoma.

Venture capitalist Seventure Partners announced that it has participated in a US$13m financing of Japanese biotech company Anaeropharma Science. The investment is made from Seventure’s Health for Life Capital investment vehicle.

Heikki Lanckriet, © Sygnis AG

German-Spanish biotech Sygnis AG has made changes to its management team and supervisory board. Heikki Lanckriet, who was previously Co-CEO, will become sole CEO of Sygnis and will also retain his role as Chief Scientific Officer.

Noxxon's study will be conducted at the National Center for Tumor Diseases in Heidelberg , ©Frank Ockert/NCT

Last December, Noxxon Pharma AG signed an agreement with Merck & Co./MSD to evaluate the synergistic potential of NOXA1/2 and pembrolizumab immune cancer therapy. Now, the companies have kicked off a Phase I/II study in patients with pancreatic and colorectal cancer.