Clive Mason is Senior Director, Anti-Infectives Research at Summit Therapeutics. He holds a leadership role in fully exploiting the Discuva platform to bring forward differentiated, new chemotype antimicrobials with novel mechanism of action against urgent-threat pathogens. Previously, he was founding scientist and Director of Biology at Discuva Ltd. Clive is a member of the BEAM Alliance* Board, where he looks to support and develop incentives for SMEs to deliver the commercial changes needed for innovative products addressing AMR.

The recently released IACG report testifies that the antimicrobial resistance (AMR) problem is now receiving some echo at the political level. Literature exploring ways to fix the acknowledged market failure is growing. Stakeholder meetings deciphering the impact of the proposed models are being organised all over the world. Still, time is against us.

A cullin-RING ubiquitin ligase, silenced in the right hemisphere, inhibits the Lewy body-like pathology triggered by exogenous alpha-Synuclein fibrils.
© Natalia Prymaczok and Juan Gerez, Science Translat. Med. doi: 10.1126/scitranslmed.aau6722

An enzyme that clears out alpha-synuclein from neurons may counteract Parkinson’s Disease, report researchers from ETH Zürich and Novartis.

© 123rf.com/Kateryna Kon

Under a partnering ageement with CEPI, Themis Bioscience will receive $21m to push pivotal testing of MV-CHIK, its Chikungunya vaccine candidate.

© 123rf.com/kletr

A fungus that produces an insecticide can stop the spread of Anopheles mosquito, which causes malaria.

© Abacus Medicine

European pharmaceutical parallel trade company Abacus Medicine A/S has postponed its planned Initial Public Offering (IPO), due to "unfavourable market environment". 

Dr. Dietmar Berger. Picture: Sanofi

Sanofi has a new head of development, which the company confirmed on Wednesday with a short tweet: "Dietmar Berger, MD, PhD, joins #Sanofi as Head of Development, overseeing our clinical portfolio across all therapeutic areas and helping us bring transformative new medicines to patients."

Thpmas Blomquist. Picture: Biotage

Tomas Blomquist has been appointed as the new CEO and President of Biotage AB.

The study authors include Charles de Bock (left), Jan Cools, Roger Habets, and Bart De Strooper.
© VIB

A Belgian-British-Australian research team has created a safer version of a therapy that combats the aggressive form of a blood cancer called acute lymphoblastic leukemia (ALL) while avoiding toxicity.

Ratio of nanomedicine accumulated or cleared in the liver (red) or delivered to the target site (green). © Curadigm

Cancer-focussed Nanobiotix SA has spun out Curadigm, which offers a platform to improve the bioavailability of nanomedicines by reducing liver and spleen toxicity and accumulation.

123rf.com/Sebastian Kaulitzki

It was a good day for Novartis: A second drug with huge selling potential has been approved for the US market. The FDA gave the go ahead for breast cancer drug Piqray (alpelisib), the first and only treatment developed specifically for patients with a PIK3CA mutation in HR+/HER2-advanced breast cancer.