
uniqure delivers POC for hemophilia B gene therapy
AMT-061, an AAV5 vector, expresses a gene cassette with the Padua variant of Factor IX, which lacks in hemophilia B patients. According to uniqure,...

New cheap CRS-blockers at the horizon
In mice, the team headed by Bert Vogelstein and Shibin Zhou from Johns-Hopkins University in Baltimore demonstrated that severe...

Reprogrammed pancreatic cells cure type I diabetes
Typically, only pancreatic beta, which lack in people with type I diabetes, cells can produce insulin. Pedro Herrera and colleagues investigated...

Adrenomed bags €24m in growth financing
The company said it will use the proceeds to advance clinical testing of adrecizumab, the companies first-in-class antibody targeting endothelial...

Diverse cells make up the endothelium
Endothelial dysfunction has been recently highlighted as a hallmark in many severe disorders including cardiovascular diseases. However,...

Uncommon mutations affect breast cancer prognosis
Patients with oestrogen receptor positive breast cancer often relapse after 5 years of later. To find out more the researchers applied targeted...

GSK swallows Tesaro in US$5.1bn deal
In 2014 GlaxoSmithKline handed its oncology portfolio to Novartis in a US$16bn deal. Though the take-over appeared like a reentry the highly...